Optic Nerve Injuries

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Optic Nerve Injuries trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 14 trials

RecruitingNot Applicable

NCT06105892

Eye Recovery Automation for Post Injury Dysfunction (iRAPID)

This study will test a portable virtual reality (VR) system with integrated eye tracking called Virtual Eye Rotation Vision Exercises (VERVE). The proposed VERV…

United States100 participantsStarted 2023-10-23

Treatment: Virtual Eye Rotation Vision Exercise (VERVE), Sham VR Therapy

RecruitingNot Applicable

NCT03233646

Retinal Imaging in Neurodegenerative Disease

This study aims to develop and evaluate biomarkers using non-invasive optical coherence tomography (OCT) and OCT angiography (OCTA) as well as ultra-widefield (…

United States2,000 participantsStarted 2017-07-20

Treatment: Retinal and Choroidal Imaging

RecruitingPhase 1

NCT06886737

Home-based Vision Therapy

Post-concussive vision symptoms affect many Veterans who have experienced traumatic brain injury (TBI). One common issue is trouble with near vision, a problem…

United States45 participantsStarted 2026-01-14

Treatment: Virtual-reality convergence training game

RecruitingPhase 1

NCT06022029

A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients…

A phase 1, multicenter, open label, non-randomized dose escalation and dose expansion study to examine the maximum tolerated dose, (MTD), minimum effective dose…

United States168 participantsStarted 2023-10-13

Treatment: ONM-501, Cemiplimab

RecruitingNot Applicable

NCT07282691

Validation of Clinical Outcome Measures Specific to mTBI-Related Oculomotor Disorders

The specific aim of this project is to validate clinical tests to be used as outcome measures in studies of mTBI-related vision problems.

United States150 participantsStarted 2025-04-01

RecruitingNot Applicable

NCT06979700

Early WAKE-up Predictors After Out-of-Hospital Cardiac Arrest

WAKE-OHCA is a prospective observational substudy of the Danish Out-of-Hospital Cardiac Arrest (DANOHCA) trial, identifier NCT05895838. The aim is to collect ea…

Denmark250 participantsStarted 2025-05-13

Treatment: Automated Pupillometry, Transcranial Doppler Ultrasound

All recent trials (84 shown)

Not Yet RecruitingPhase 4

NCT07240649

Outcomes From Hyperbaric Oxygen (HBO2) Treatment for Emerging Indications

This study will evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) on treating emerging indications (i.e., conditions that have shown to potentially…

Location not specified100 participantsStarted 2026-08

Treatment: Hyperbaric oxygen treatment (HBOT), 100% Oxygen

CompletedNot Applicable

NCT06946030

Pseudoexfoliation and Carpal Tunnel Study

This prospective, single-center case-control study aimed to investigate the association between pseudoexfoliation syndrome (PES) and carpal tunnel syndrome (CTS…

Turkey (Türkiye)159 participantsStarted 2025-05-01

Optic Nerve Injuries

Trial phase breakdown

Trial status

Actively recruiting — 14 trials

Eye Recovery Automation for Post Injury Dysfunction (iRAPID)

Retinal Imaging in Neurodegenerative Disease

Home-based Vision Therapy

A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients…

Validation of Clinical Outcome Measures Specific to mTBI-Related Oculomotor Disorders

Early WAKE-up Predictors After Out-of-Hospital Cardiac Arrest

All recent trials (84 shown)

Outcomes From Hyperbaric Oxygen (HBO2) Treatment for Emerging Indications

Pseudoexfoliation and Carpal Tunnel Study

Trial phase breakdown

Trial status

Actively recruiting — 14 trials

Eye Recovery Automation for Post Injury Dysfunction (iRAPID)

Retinal Imaging in Neurodegenerative Disease

Home-based Vision Therapy

A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients…

Validation of Clinical Outcome Measures Specific to mTBI-Related Oculomotor Disorders

Early WAKE-up Predictors After Out-of-Hospital Cardiac Arrest

All recent trials (84 shown)

Outcomes From Hyperbaric Oxygen (HBO2) Treatment for Emerging Indications

Pseudoexfoliation and Carpal Tunnel Study

Evaluation of Supraclavicular Brachial Plexus Blocks at Various Volumes: Impact on Optic Nerve Sheath Diameter

Persistent Post-Concussion Symptoms With Convergence Insufficiency

Incremental Velocity Error as a New Treatment in Vestibular Rehabilitation

Corneal Nerves Function and Structure

Clinical Trial Comparing Two Non-Surgical Treatments for Severe Blepharoptosis

Diagnostic Accuracy of the Optic Nerve Deformability Index and Optic Nerve Sheath Diameter as a Noninvasive Predictor of…

Early Check: Expanded Screening in Newborns

Trial of Parkinson's And Zoledronic Acid

Natural History of MTBI-related Convergence Insufficiency & Effectiveness of Vision Therapy for MTBI-related CI

Assessment of Intracranial Pressure Using Optic Nerve Sheath Diameter in Head Trauma in Assiut University

Effects of Cervical Hyperextension on Cervical Blood Flow, Cerebral Oximetry and Cognitive Functions.

Effect of Spinal Needle Type on Optic Nerve Sheath Diameter

Optic Nerve Stimulation To Prevent Visual Deficits After Endoscopic Cranial Approaches

Epidural Stimulation for Upper Extremity Function

Traumatic Optic Neuropathy Treatment Trial 2

Axial Length and Central Corneal Thickness in Benign Intracranial Hypertension

Intracranial Pressure and Optic Nerve Sheath Diameter With CLOSED Bundle

Neurological Dry Eye Study Stimulating Both Lacrimal and Vagus Nerves