Clinical Trial Comparing Two Non-Surgical Treatments for Severe Blepharoptosis

Inclusion Criteria: * Presence of ptosis for at least one eye which occludes the visual axis in the resting position (without frontalis drive, lifting with forehead muscles) * Moderate cognitive function or better defined as greater than or equal to 18 out of 30 on a pre-screening of the Mini-Mental State Exam (MMSE) Exclusion Criteria: * Absence of ptosis which occludes the visual axis * Presence of a corneal ulcer of any size * Age less than 5 years * Severe Cognitive impairment defined as MMSE score less than 18, behaviors consistent with delirium (combinations of disorientation, hallucinations, delusions, and incoherent speech), or lethargy. * Presence of corneal hypoaesthesia; * Orbicularis weakness on the side of the ptosis * Mechanical ptosis, including ptosis due to orbital or lid tumor, cicatricial processes affecting the movements of the upper lid, and enophthalmos. * Previous ptosis surgery less than 3 months prior to Visit 1. * Lid position affected by lid or conjunctival scarring. * History of herpes keratitis. * Periocular neurotoxin (eg, Botox, Xeomin, Dysport, Myobloc) injections on the side of the ptosis within 3 months prior to Visit 1 and during the study. * History of hyperthyroidism or thyroid eye disease (ie, exophthalmos, upper eyelid retraction, diplopia secondary to extraocular muscle involvement). Hypothyroidism that is controlled on medication is allowed