Cancer

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Cancer trials you may qualify for

100

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 56 trials

RecruitingPhase 1

NCT05005403

Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck…

Cancer is a condition where cells in a specific part of body grow and reproduce uncontrollably. Non-Small Cell Lung Cancer (NSCLC) is a solid tumor, a disease i…

United States694 participantsStarted 2021-11-01

Treatment: Azirkitug, Budigalimab

RecruitingPhase 1/2

NCT07147231

Testing the Effectiveness of the Anti-cancer Drug Pidnarulex (CX-5461), in Combination With Another Anti-cancer Drug Cem…

This phase I/II trial studies the side effects and best dose of pidnarulex when given together with cemiplimab and to see how well it works in treating patients…

United States86 participantsStarted 2026-12-21

Treatment: Biopsy Procedure, Biospecimen Collection

RecruitingPhase 3

NCT04181060

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

This phase III trial compares the effect of bevacizumab and osimertinib combination vs. osimertinib alone for the treatment of non-small cell lung cancer that h…

United States300 participantsStarted 2020-12-28

Treatment: Bevacizumab, Biospecimen Collection

RecruitingNot Applicable

NCT06856733

Improved Treatment for Patients With Long-term Opioid Therapy for Non-cancer Pain in Primary Care

The goal of this clinical trial is to reduce inappropriate long term opioid treatment (LTOT) and to optimize pain management in patients with LTOT for chronic n…

Sweden110 participantsStarted 2025-03-10

Treatment: Person-centred team-based approach

RecruitingPhase 2

NCT06770582

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy T…

This phase II trial compares the use of pembrolizumab and radiation therapy to chemotherapy with cisplatin, gemcitabine, 5-fluorouracil or mitomycin-C and radia…

United States160 participantsStarted 2025-06-03

Treatment: Biospecimen Collection, Cisplatin

RecruitingPhase 1/2

NCT05896839

Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metasta…

This phase II trial tests the combination of nivolumab and ipilimumab with sirolimus and prednisone for the treatment of skin (cutaneous) cancer that cannot be…

United States16 participantsStarted 2024-07-24

Treatment: Biopsy Procedure, Biospecimen Collection

All recent trials (100 shown)

Not Yet RecruitingPhase 2

NCT07516366

Testing the Safety and Feasibility of Immunotherapy Drugs, Botensilimab and Balstilimab, Before Surgery for Clear Cell R…

This phase II trial tests the effect of botensilimab and balstilimab before surgery (neoadjuvant) in treating patients with high-risk clear cell renal cell canc…

Location not specified16 participantsStarted 2026-06-04

Treatment: Balstilimab, Biospecimen Collection

Active — Not RecruitingPhase 1

NCT03030378

Pembrolizumab and Recombinant Interleukin-12 in Treating Patients With Solid Tumors

This phase I trial studies the side effects and best dose of pembrolizumab and recombinant interleukin-12 in treating patients with solid tumors. Immunotherapy…

United States36 participantsStarted 2018-05-30

Treatment:

Cancer

Trial phase breakdown

Trial status

Actively recruiting — 56 trials

Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck…

Testing the Effectiveness of the Anti-cancer Drug Pidnarulex (CX-5461), in Combination With Another Anti-cancer Drug Cem…

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

Improved Treatment for Patients With Long-term Opioid Therapy for Non-cancer Pain in Primary Care

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy T…

Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metasta…

All recent trials (100 shown)

Testing the Safety and Feasibility of Immunotherapy Drugs, Botensilimab and Balstilimab, Before Surgery for Clear Cell R…

Pembrolizumab and Recombinant Interleukin-12 in Treating Patients With Solid Tumors

Trial phase breakdown

Trial status

Actively recruiting — 56 trials

Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck…

Testing the Effectiveness of the Anti-cancer Drug Pidnarulex (CX-5461), in Combination With Another Anti-cancer Drug Cem…

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

Improved Treatment for Patients With Long-term Opioid Therapy for Non-cancer Pain in Primary Care

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy T…

Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metasta…

All recent trials (100 shown)

Testing the Safety and Feasibility of Immunotherapy Drugs, Botensilimab and Balstilimab, Before Surgery for Clear Cell R…

Pembrolizumab and Recombinant Interleukin-12 in Treating Patients With Solid Tumors

Virtual Reality in Reducing Pain and Anxiety in Cancer Participants Undergoing Painful Procedures

A Phase Ⅰ Study of CS08399 in Participants With MTAP-deleted Solid Tumors and Lymphoma

Confocal Laser Endomicroscopy Nodule Localization by Robotic Bronchoscopy

Testing the Addition of an Anti-cancer Drug, M3814, to the Usual Treatment (Mitoxantrone, Etoposide, and Cytarabine) for…

Dabrafenib and Lapatinib in Treating Patients With Refractory Thyroid Cancer That Cannot Be Removed by Surgery

Sapanisertib in Treating Patients With Locally Advanced or Metastatic Bladder Cancer With TSC1 and/or TSC2 Mutations

An Extension Study of Venetoclax for Subjects Who Have Completed a Prior Venetoclax Clinical Trial

Phase 2B Safety and Efficacy Study of VGT-309 in Subjects With Cancer in the Lung.

CI Following VS Removal or Labyrinthectomy

Testing the Addition of Anti-cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment, Cetuximab Plus Encorafenib, fo…

Testing the Addition of the Pill Chemotherapy, Cabozantinib, to the Standard Immune Therapy Nivolumab Compared to Standa…

A Phase 1 First-in-Human Study of CRPA1A2, a MAGE-A1/HLA-A*02:01 Bispecific T-Cell Engager, in Patients With Solid Tumor…

NCI COVID-19 in Cancer Patients, NCCAPS Study

A Study to Investigate Velzatinib Compared With Imatinib in Adult Participants With Previously Untreated Metastatic and/…

Testing the Combination of an Anti-Cancer Drug, Iadademstat, With Other Anti-Cancer Drugs (Venetoclax and Azacitidine) f…

Testing the Addition of an Anti-cancer Drug, Pembrolizumab, to the Usual Intravesical Chemotherapy Treatment (Gemcitabin…

Testing the Effect of M1774 on Hard-to-Treat Refractory SPOP-mutant Prostate Cancer

Testing MK-3475 (Pembrolizumab) After Surgery for Localized Muscle-Invasive Bladder Cancer and Locally Advanced Urotheli…