A Phase I Feasibility Study of an Intracortical Visual Prosthesis (ICVP) for People With Blindness

Inclusion Criteria: * No light perception or bare light perception, in each eye in accordance with relevant International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) codes, where the physician has no expectation of improvement through currently approved treatments. * History of normal or near-normal vision, with or without refractive correction, during at least the first 10 years of life. * Adjusted to blindness for at least one year. * History of vision or blindness rehabilitation. * Willing and able to meet the time demands of the study with transportation assistance. * Willing to agree to audio and video recording, as specified in the pre-screening consent. * Motivated by altruism, willingness to participate in pioneering science. * Demonstrated support from spouse, family and/or friends. * High or average cognitive and spatial functioning. * Normal structural MRI. * English as preferred language. * Normal decision-making capacity. Exclusion Criteria: * Poor adjustment to blindness, or vision loss within the last year. * Expectation of vision restoration to pre-blindness level through trial participation. * History of alcohol or drug dependence. * Evidence of prior immune response to an orthopedic implant which caused the implant to be explanted * A disease prognosis of living less than five years. * An implant which would prevent screening using MRI, or a pacemaker, or similar implant. * A history of seizures. * Current suicidal ideati…