Addison's Disease

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Addison's Disease trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 5 trials

RecruitingNot Applicable

NCT05368090

Endoscopic Ultrasound-guided Radiofrequency Ablation in Primary Aldosteronism

In this study, the investigators will perform endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) treatment of left-sided adrenal tumours in patients…

Norway60 participantsStarted 2022-06-03

Treatment: EUS-RFA of left adrenal tumour in PA with AVS-verified left lateralisation, EUS-RFA of left adrenal tumour in PA, "debulking group"

RecruitingNot Applicable

NCT04885179

SPL Insufficiency Syndrome (SPLIS)/NPHS14: a SPLIS Observational Study and Patient Registry (International)

This protocol aims to gather information about sphingosine phosphate lyase insufficiency syndrome (SPLIS), also known as NPHS14, and to create a SPLIS patient r…

United States120 participantsStarted 2025-04-22

Treatment: no intervention

RecruitingNot Applicable

NCT04569149

Primordial Dwarfism Registry

The goal of this registry is to collect information on individuals with forms of microcephalic primordial dwarfism as well as related conditions. The study team…

United States200 participantsStarted 2008-03-11

RecruitingNot Applicable

NCT01793168

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, i…

United States, Australia20,000 participantsStarted 2010-07

RecruitingNot Applicable

NCT06669949

Natural History of Sphingosine Phosphate Lyase Insufficiency Syndrome (SPLIS)

This is a prospective longitudinal natural history study with a retrospective cross-sectional arm aimed at determining the natural history of sphingosine phosph…

United States28 participantsStarted 2025-04-22

Treatment: no intervention

All recent trials (41 shown)

Active — Not RecruitingNot Applicable

NCT03793114

Screening and Stimulation Testing for Residual Secretion of Adrenal Steroid Hormones in Autoimmune Addison's Disease

In autoimmune adrenal insufficiency, or Addison's disease (AD), the immune system attacks the adrenal cortex. As a result, the adrenal cells producing hormones…

Germany, Norway, Sweden200 participantsStarted 2018-09-26

Treatment: Cosyntropin stimulation test, Baseline blood tests

Not Yet RecruitingNot Applicable

NCT07413874

Telehealth Music Therapy for Adults With Endocrine Disorder and Depression

The goal of this clinical trial is to explore if a telehealth music therapy intervention helps with quality of life, depression symptoms, anxiety symptoms. It w…

Location not specified10 participantsStarted 2026-02-01

Treatment: Telehealth Resource Oriented Music Therapy

Addison's Disease

Trial phase breakdown

Trial status

Actively recruiting — 5 trials

Endoscopic Ultrasound-guided Radiofrequency Ablation in Primary Aldosteronism

SPL Insufficiency Syndrome (SPLIS)/NPHS14: a SPLIS Observational Study and Patient Registry (International)

Primordial Dwarfism Registry

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

Natural History of Sphingosine Phosphate Lyase Insufficiency Syndrome (SPLIS)

All recent trials (41 shown)

Screening and Stimulation Testing for Residual Secretion of Adrenal Steroid Hormones in Autoimmune Addison's Disease

Telehealth Music Therapy for Adults With Endocrine Disorder and Depression

Trial phase breakdown

Trial status

Actively recruiting — 5 trials

Endoscopic Ultrasound-guided Radiofrequency Ablation in Primary Aldosteronism

SPL Insufficiency Syndrome (SPLIS)/NPHS14: a SPLIS Observational Study and Patient Registry (International)

Primordial Dwarfism Registry

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

Natural History of Sphingosine Phosphate Lyase Insufficiency Syndrome (SPLIS)

All recent trials (41 shown)

Screening and Stimulation Testing for Residual Secretion of Adrenal Steroid Hormones in Autoimmune Addison's Disease

Telehealth Music Therapy for Adults With Endocrine Disorder and Depression

Risks of Ramadan Fasting in Patients With Primary Adrenal Insufficiency Treated With Prednisolone.

A Study of Markers of Glucocorticoid Effects in Patients With Addisons Disease (DOSCORT)

Risks of Intermittent Fasting in Patients With Primary Adrenal Insufficiency

Ultradian Subcutaneous Hydrocortisone Infusion in Addison Disease and Congenital Adrenal Hyperplasia

Chronocort Versus Plenadren Replacement Therapy in Adults With Adrenal Insufficiency

Residual Adrenal Function in Addison's Disease

Continuous Subcutaneous Hydrocortisone Infusion In Addison's Disease and Type 1 Diabetes

Growing up With the Young Endocrine Support System (YESS!)

Does Relative Hypoglycaemia &/or Sleep Disturbance Contribute to the Lethargy Observed in Addison's Disease

Clinical Study on Circadian Genes Dysregulation in Patients With Glucocorticoid Disorders

The Effects of Two Brands of Hydrocortisone Injected Intramuscularly Into Deltoid and Thigh Muscles

Biomarker(s) for Glucocorticoids

Additional Autoimmune Diseases With Type 1 Diabetes in Pediatrics at Diabetes Diagnosis and During Follow-up

Once-daily Oral Modified Release Hydrocortisone in Patients With Adrenal Insufficiency

Spontaneous Coronary Artery Dissection (SCAD) and Autoimmunity

Dual RElease Hydrocortisone Versus conventionAl Glucocorticoid replaceMent Therapy in Hypocortisolism (DREAM)

Cardiovascular Status in Adrenal Insufficiency

Vaginal Prednisone Administration for Prevention of Adrenal Crisis