CompletedNot Applicable

Cardiovascular Status in Adrenal Insufficiency

Germany68 participantsStarted 2013-08

Plain-language summary

Within this trial, the cardiovascular status and metabolic profile of patients with chronic primary adrenal insufficiency is evaluated.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Chronic primary adrenal insufficiency * Adequate hormone replacement therapy (\>3 years) * Age \>18 years * Patient's informed consent Exclusion Criteria: * Hormone replacement therapy with an other glucocorticoid than hydrocortisone * Pharmacotherapy with glucocorticoids * Congenital adrenal hyperplasia * Coronary heart disease * Heart failure * Systemic disease with (potential) cardiac involvement (e.g. amyloidosis, lung fibrosis) * Pregnancy * Chronic alcohol abuse * Malignant disease * Arterial hypertension * Chronic renal failure (MDRD \<60)

What they're measuring

Cardiovascular status - anamnesis

Timeframe: 12 months

Cardiovascular status - mean systolic blood pressure

Timeframe: 12 months

Cardiovascular status - mean diastolic blood pressure

Timeframe: 12 months

Cardiovascular status - mean BMI

Timeframe: 12 months

Cardiovascular status - mean HbA1c

Timeframe: 12 months

Cardiovascular status - mean cholesterol-level

Timeframe: 12 months

Cardiovascular status - mean triglyceride-level

Timeframe: 12 months

Cardiovascular status - reactive hyperaemia index

Timeframe: 12 months

Trial details

NCT IDNCT03426319

SponsorWuerzburg University Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2014-06

View on ClinicalTrials.gov More Adrenal Insufficiency trials