CompletedNot Applicable

Risks of Intermittent Fasting in Patients With Primary Adrenal Insufficiency

Tunisia30 participantsStarted 2024-03-04

Plain-language summary

In primary adrenal insufficiency, there is an increased risk of hypoglycaemia and dehydration. These risks have been little studied particularly during intermittent fasting. The present study aimed to assess these risks in a prospective study of 30 subjects with primary adrenal insufficiency. Patients will undergo a clinical examination, blood sampling and continuous glucose monitoring for fourteen days (one week of fasting and one week of non-fasting).

Who can participate

Age range20 Years – 65 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Primary adrenal insufficiency * Disease duration of at least one year * Substituted with hydrocortisone and fludrocortisone * Wishing to fast during the month of Ramadan 2024 Exclusion Criteria: * Diabetes mellitus * Renal insufficiency * Hepatic insufficiency * Cardiac insufficiency * Respiratory insufficiency * Use of hypoglycaemic agents * Use of diuretics * Use of glucocorticoids other than those prescribed for replacement * Poor control of the disease (asthenia, malaise, melanoderma, discontinuation of treatment, etc.) * Pregnancy * Breast-feeding.

What they're measuring

hypoglycemia

Timeframe: the fasting period from predawn to sunset (approximately 16 hours)

Trial details

NCT IDNCT06299020

SponsorHopital La Rabta

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-04-20

View on ClinicalTrials.gov More Primary Adrenal Insufficiency trials