ICU Acquired Weakness

Clinical trial pipeline · Data from ClinicalTrials.gov

See which ICU Acquired Weakness trials you may qualify for

100

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 30 trials

RecruitingNot Applicable

NCT05218083

REmotely Monitored, Mobile Health Supported Multidomain Rehabilitation Program With High Intensity Interval Training for…

Multicenter, prospective, randomized controlled trial providing mobile health supported physical rehabilitation to 120 patients who have been critically ill wit…

United States120 participantsStarted 2023-02-23

Treatment: REmotely monitored, Mobile health supported Multidomain Rehabilitation Program with High Intensity Interval Training (REMM-HIIT)

RecruitingNot Applicable

NCT07017517

NLRP3 Inflammasome and Physical Therapy in ICU-Acquired Weakness

The goal of this clinical trial is to study whether physical therapy can reduce NLRP3 inflammasome activation and muscle atrophy in patients with critical illne…

Chile24 participantsStarted 2026-04-20

Treatment: Motomed Letto® servo-assisted cycling + standard physiotherapy, Standard physiotherapy

RecruitingNot Applicable

NCT07489092

Feasibility of a Digital Rehabilitation Platform in Patients After ICU Discharge

This study aims to evaluate the feasibility, usability, and clinical effectiveness of a digital rehabilitation platform in adult patients discharged from the in…

South Korea70 participantsStarted 2026-02-02

Treatment: Digital Rehabilitation Group

RecruitingNot Applicable

NCT04658498

Improving Our Understanding of Respiratory Muscle Training to Facilitate Weaning From Mechanical Ventilation in the ICU

Mechanical ventilation is a life-saving treatment frequently applied in intensive care unit (ICU). Nonetheless, by putting at rest the respiratory muscles, it c…

Belgium90 participantsStarted 2023-02-01

Treatment: Procedure: Usual Care (UC), Procedure: UC + HI-IMT

RecruitingNot Applicable

NCT05279547

Locomotor Muscle Oxygenation and Activation During Acute Interval Compared to Constant-load Bed-cycling Exercise

Up to 60% of patients admitted to the Intensive Care Unit (ICU) with a prolonged stay in the ICU develop complications such as intensive care unit acquired weak…

Belgium100 participantsStarted 2023-02-01

Treatment: Constant-load bed-cycling exercise, Interval bed-cycling exercise

RecruitingNot Applicable

NCT04989790

Clinical Effectiveness of the "PICU Up!" Multifaceted Early Mobility Intervention for Critically Ill Children

While mortality in U.S. pediatric intensive care units (PICUs) is improving, surviving children frequently develop persistent physical, cognitive, and psycholog…

United States1,440 participantsStarted 2022-08-08

Treatment: PICU Up!

All recent trials (100 shown)

CompletedNot Applicable

NCT07336810

Whole-Body Vibration Versus Neuro Muscular Electrical Stimulation on Patients With ICU Acquired Weakness

Purpose: to investigate the effect of Whole-body vibration versus neuro-muscular electrical stimulation on patients with intensive care-acquired weakness. Metho…

Egypt60 participantsStarted 2026-01-10

Treatment: whole body VIBRATION Viberation, Neuro muscular electrical stimulation

Not Yet RecruitingEarly Phase 1

NCT05326633

Effect of Protein, Mobility Therapy and Electric Stimulation on Recovery in Older ICU Survivors

Older ICU survivors with ICU acquired weakness (ICUAW) are malnourished, sarcopenic, and functionally debilitated as a consequence of the high burden of comorbi…

United States78 participantsStarted 2027-03-01

Treatment: MRP and High Protein Supplement (HPRO) and Neuromuscular Electric Stimulation (NMES)

ICU Acquired Weakness

Trial phase breakdown

Trial status

Actively recruiting — 30 trials

REmotely Monitored, Mobile Health Supported Multidomain Rehabilitation Program With High Intensity Interval Training for…

NLRP3 Inflammasome and Physical Therapy in ICU-Acquired Weakness

Feasibility of a Digital Rehabilitation Platform in Patients After ICU Discharge

Improving Our Understanding of Respiratory Muscle Training to Facilitate Weaning From Mechanical Ventilation in the ICU

Locomotor Muscle Oxygenation and Activation During Acute Interval Compared to Constant-load Bed-cycling Exercise

Clinical Effectiveness of the "PICU Up!" Multifaceted Early Mobility Intervention for Critically Ill Children

All recent trials (100 shown)

Whole-Body Vibration Versus Neuro Muscular Electrical Stimulation on Patients With ICU Acquired Weakness

Effect of Protein, Mobility Therapy and Electric Stimulation on Recovery in Older ICU Survivors

Trial phase breakdown

Trial status

Actively recruiting — 30 trials

REmotely Monitored, Mobile Health Supported Multidomain Rehabilitation Program With High Intensity Interval Training for…

NLRP3 Inflammasome and Physical Therapy in ICU-Acquired Weakness

Feasibility of a Digital Rehabilitation Platform in Patients After ICU Discharge

Improving Our Understanding of Respiratory Muscle Training to Facilitate Weaning From Mechanical Ventilation in the ICU

Locomotor Muscle Oxygenation and Activation During Acute Interval Compared to Constant-load Bed-cycling Exercise

Clinical Effectiveness of the "PICU Up!" Multifaceted Early Mobility Intervention for Critically Ill Children

All recent trials (100 shown)

Whole-Body Vibration Versus Neuro Muscular Electrical Stimulation on Patients With ICU Acquired Weakness

Effect of Protein, Mobility Therapy and Electric Stimulation on Recovery in Older ICU Survivors

Muscle Effects Of Neuromuscular Electrostimulation In Mechanically Ventilated Patients In An Icu

Feasibility and Safety of Digital Rehab Platform for Bedridden Patients

Development of an Early Warning Model for Intensive Care Unit-Acquired Weakness in Mechanically Ventilated Children

Metabolic Response to Supine Physiotherapy in Mechanically Ventilated ICU Patients

Exploring Novel Biomarkers of ICU-AW in Mechanically Ventilated Children at the Molecular Level

Critical Illness Myopathy as a Cause of Debilitating ICU-Acquired Weakness

MyokinE100 System: Closed Loop Electrical Muscle Stimulation to Mitigate ICU Acquired Weakness in Medical ICU Patients

Comparison for the Effect of Neuromuscular Blocking Agents Versus Sedation Alone on Severe ARDS Patients Due to COVID-19

Recovery of Physical Function After Critical Illness In Older Adults

Development of the Italian Version of the ICU Mobility Scale (IMS). Cross-cultural Adaptation, Italian Translation, and…

Virtual Reality in Intensive Care Unit: Patient Satisfaction, Clinical and Functional Outcomes, Feasibility

Early Assessment of Quadriceps Muscle Recovery by Dynamometry and 3D Ultrasound in Intensive Care Patients Under Invasiv…

Assessing The Effects of Exercise, Protein, and Electric Stimulation On Intensive Care Unit Patients Outcomes

Continuous Passive Motion to Prevent Ankle Contracture and Muscle Atrophy in Ventilated Patients

Using Continuous Passive Motion to Prevent Ankle Problems in ICU Patients

Effect of Arm Cycling Exercise on Pulmonary Functions After Colectomy In Elderly

Functional Recovery Over the First Year After ICU Discharge

Neuromodulation for Prevention of Intensive Care Unit Acquired Weakness and Post Intensive Care Syndrome