Anal Fissure Chronic

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Anal Fissure Chronic trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 5 trials

RecruitingNot Applicable

NCT07568314

Comparison of Botulinum Toxin Injection and Lateral Internal Sphincterotomy in Chronic Anal Fissure Management

This study aims to compare two commonly used treatments for chronic anal fissure: botulinum toxin injection and lateral internal sphincterotomy. Chronic anal fi…

Pakistan90 participantsStarted 2026-03-02

Treatment: Botulinum Toxin Type A (BOTOX) Injection, Lateral Internal Sphincterotomy

RecruitingPhase 1

NCT06456073

E-CEL UVEC Treatment for Anal Fissures

This clinical trial is being conducted by investigators who are colorectal surgeons. Eligible study participants will receive the experimental treatment E-CEL U…

United States20 participantsStarted 2024-09-12

Treatment: E-CEL UVEC cells (AB-207)

RecruitingNot Applicable

NCT07268261

Combined Method of Surgical Treatment of Anal Fissure

The purpose of this study is to improve treatment outcomes for patients with chronic anal fissure.

Russia122 participantsStarted 2023-09-01

Treatment: excision of the anal fissure with further relaxation of the internal sphincter with botulinum toxin A

RecruitingNot Applicable

NCT06803550

Effect of Enhanced Recovery After Surgery for Benign Anorectal Conditions

This study aims to assess the role of Enhanced recovery after surgery(ERAS) protocol in reducing postoperative urine retention (POUR) after surgery for benign a…

Egypt100 participantsStarted 2024-12-17

Treatment: Enhanced recovery after surgery protocol, Routine pathway

RecruitingPhase 4

NCT03855046

Complex Treatment of a Chronic Anal Fissure

This study is aimed at studying the efficacy and safety of treating chronic anal fissure with botulinum toxin versus lateral subcutaneous sphincterotomy.

Russia340 participantsStarted 2019-09-01

Treatment: IncobotulinumtoxinA 50 U Intramuscular Powder for Solution, Lateral subcutaneous sphincterotomy.

All recent trials (47 shown)

Not Yet RecruitingPhase 4

NCT07240649

Outcomes From Hyperbaric Oxygen (HBO2) Treatment for Emerging Indications

This study will evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) on treating emerging indications (i.e., conditions that have shown to potentially…

Location not specified100 participantsStarted 2026-08

Treatment: Hyperbaric oxygen treatment (HBOT), 100% Oxygen

CompletedPhase 3

NCT07543315

Low Versus High Dose OnabotulinumtoxinA for Chronic Anal Fissure

The goal of this clinical trial is to evaluate the efficacy of botulinum toxin injection in treatment of patients with chronic anal fissures comparing between t…

Egypt70 participantsStarted 2023-08-01

Treatment: injection of Botulinum type A

Anal Fissure Chronic

Trial phase breakdown

Trial status

Actively recruiting — 5 trials

Comparison of Botulinum Toxin Injection and Lateral Internal Sphincterotomy in Chronic Anal Fissure Management

E-CEL UVEC Treatment for Anal Fissures

Combined Method of Surgical Treatment of Anal Fissure

Effect of Enhanced Recovery After Surgery for Benign Anorectal Conditions

Complex Treatment of a Chronic Anal Fissure

All recent trials (47 shown)

Outcomes From Hyperbaric Oxygen (HBO2) Treatment for Emerging Indications

Low Versus High Dose OnabotulinumtoxinA for Chronic Anal Fissure

Trial phase breakdown

Trial status

Actively recruiting — 5 trials

Comparison of Botulinum Toxin Injection and Lateral Internal Sphincterotomy in Chronic Anal Fissure Management

E-CEL UVEC Treatment for Anal Fissures

Combined Method of Surgical Treatment of Anal Fissure

Effect of Enhanced Recovery After Surgery for Benign Anorectal Conditions

Complex Treatment of a Chronic Anal Fissure

All recent trials (47 shown)

Outcomes From Hyperbaric Oxygen (HBO2) Treatment for Emerging Indications

Low Versus High Dose OnabotulinumtoxinA for Chronic Anal Fissure

Comparison of Lateral Internal Sphincterotomy Techniques for Chronic Anal Fissure

Closed Versus Open Lateral Internal Sphincterotomy for Chronic Anal Fissure

RELIEF Study: Resolving Fissures With Lateral Internal Sphincterotomy

Short-Term Outcome of Medical Vs. Surgical Management Of Chronic Anal Fissure

Effect of Phenytoin Cream on Wound Healing After Anal Fissure Surgery.

The Efficacy of Botulinum Toxin Alone Versus Combined Botulinum Toxin and Topical Diltiazem in Chronic Anal Fissure

Percutaneous Tibial Nerve Stimulation (PTNS) for the Treatment of Chronic Anal Fissure

The Use of Platelet-rich Plasma in the Treatment of Chronic Anal Fissure

Comparison of Injections of Botulinum Toxin and Topical Nitroglycerin Ointment for the Treatment of Chronic Anal Fissure

Efficacy and Safety of Propionibacterium Extract Gel Versus 0.4% Glyceryl Trinitrate Ointment in the Treatment of Chroni…

Botulinum Toxin Type A in the Treatment of Chronic Anal Fissure

Microbiota in Chronic Anal Fissure and Its Association With Prognosis

Short Term Results of Platelet-rich Plasma in the Treatment of Chronic Anal Fissure

Surgical Treatment of a Chronic Anal Fissure

Diltiazem Ointment With Lidocaine vs. Nifedipine Ointment With Lidocaine Ointment for Treatment of Chronic Anal Fissure

Effect of Shock Waves Therapy on Chronic Anal Fissure

Sungurtekin Technique vs. Closed Lateral Internal Sphincterotomy Technique

Postero-lateral Internal Sphincterotomy vs Botulinum Toxin Injection in the Treatment of Chronic Anal Fissure