CompletedPhase 1/2

Short-Term Outcome of Medical Vs. Surgical Management Of Chronic Anal Fissure

Egypt99 participantsStarted 2024-08-30

Plain-language summary

Several topical agents have been proposed for Chronic anal fissure (CAF) treatment with the common goal of increasing anodermal blood flow to promote healing but approaching the use of medical treatment in CAFs is not standardized yet. Thus, the present study aimed to compare the efficacy and safety of Sucralfate (Emoflon®), the combination of azadirachtin and hyperforin (HyperOil®) and the traditional surgical treatment (lateral sphincterotomy) in patients with CAFs.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * above 18 years old. * CAFs for the first time * ASA I, II Exclusion Criteria: * Sepsis * Previous pelvic radiation. * recurrent chronic anal fissure * Pregnancy or lactation. * Immunosuppressive state * Malignancy * Refusal to participate

What they're measuring

REALISE score

Timeframe: in each 3 follow up visits (visit 1,2, and 3 after 15, 30 , and 40 days respectively)

Trial details

NCT IDNCT06617026

SponsorSuez Canal University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-10-01

View on ClinicalTrials.gov More Anal Fissure Chronic trials