Vision; Disorder, Loss

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Vision; Disorder, Loss trials you may qualify for

100

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 44 trials

RecruitingNot Applicable

NCT05355415

Adaptive Optics Imaging of Outer Retinal Diseases

The objective of the study is to collect adaptive optics (AO) retinal images from human subjects with outer retinal diseases (diseases of the outer retina inclu…

United States100 participantsStarted 2021-08-27

Treatment: Adaptive optics imaging

RecruitingNot Applicable

NCT07548944

Observational Study to Investigate the Short-term Effects of Transcorneal Electrical Stimulation on Visual Performance

Retinitis pigmentosa and similar degenerative diseases of the retina lead to progressive loss of vision. TES therapy with the CE-marked OkuStim® System is a tre…

Germany30 participantsStarted 2026-04-20

Treatment: Transcorneal Electrical Stimulation using the OkuStim System

RecruitingNot Applicable

NCT07015034

Developing and Testing a Model to Identify Preventive Vision Loss Among Older Patients in General Practice

In this cohort study, the investigators will test vision screenings in Danish general practice for patients over 70 years of age with minimum one chronic condit…

Denmark460 participantsStarted 2024-05-15

Treatment: focus on vision impairment in older patients in general practice

RecruitingNot Applicable

NCT03848663

Visual Remapping to Aid Reading With Field Loss

Reading performance in patients with Central Vision Loss and age matched controls with artificial scotomas will be measured with and without different kinds of…

United States108 participantsStarted 2022-02-01

Treatment: Traditional Remapping, Personalized Remapping

RecruitingPhase 1/2

NCT06789445

A Study to Investigate the Safety of OpCT-001 in Adults Who Have Primary Photoreceptor Disease (CLARICO)

Study OpCT-001-101 is a Phase 1/2a first-in-human, multisite, 2-part interventional study to evaluate the safety, tolerability, and the effect on clinical outco…

United States54 participantsStarted 2025-03-10

Treatment: OpCT-001, OpCT-001

RecruitingNot Applicable

NCT07185971

PAVE (Parallactic Visual-Field Enhancement) System for Treatment of Chronic Visual Field Loss Due to Stroke, Traumatic B…

This is a research study to evaluate the effectiveness of the PAVE (Parallactic Visual-Field Enhancement) System for the treatment of chronic visual field loss…

United States20 participantsStarted 2026-03-16

Treatment: PAVE (Parallactic Visual-Field Enhancement) treatment using a virtual reality head mounted display

All recent trials (100 shown)

CompletedPhase 2

NCT03717909

Efficacy and Safety Trial of Sodium Valproate, in Paediatric and Adult Patients With Wolfram Syndrome

This trial aims to investigate the efficacy, safety and tolerability of sodium valproate in the treatment of patients with Wolfram syndrome. 70 paediatric and a…

France, Poland +2 more63 participantsStarted 2018-12-28

Treatment: Sodium Valproate 200Mg E/C Tablet, Sodium Valproate matched placebo

Active — Not RecruitingPhase 3

NCT05537220

Oral N-acetylcysteine for Retinitis Pigmentosa

Retinitis pigmentosa (RP) is an inherited retinal degeneration caused by one of several mistakes in the genetic code. Such mistakes are called mutations. The mu…

United States485 participantsStarted 2023-10-11

Treatment: N-acetylcysteine, Placebo

Vision; Disorder, Loss

Trial phase breakdown

Trial status

Actively recruiting — 44 trials

Adaptive Optics Imaging of Outer Retinal Diseases

Observational Study to Investigate the Short-term Effects of Transcorneal Electrical Stimulation on Visual Performance

Developing and Testing a Model to Identify Preventive Vision Loss Among Older Patients in General Practice

Visual Remapping to Aid Reading With Field Loss

A Study to Investigate the Safety of OpCT-001 in Adults Who Have Primary Photoreceptor Disease (CLARICO)

PAVE (Parallactic Visual-Field Enhancement) System for Treatment of Chronic Visual Field Loss Due to Stroke, Traumatic B…

All recent trials (100 shown)

Efficacy and Safety Trial of Sodium Valproate, in Paediatric and Adult Patients With Wolfram Syndrome

Oral N-acetylcysteine for Retinitis Pigmentosa

Trial phase breakdown

Trial status

Actively recruiting — 44 trials

Adaptive Optics Imaging of Outer Retinal Diseases

Observational Study to Investigate the Short-term Effects of Transcorneal Electrical Stimulation on Visual Performance

Developing and Testing a Model to Identify Preventive Vision Loss Among Older Patients in General Practice

Visual Remapping to Aid Reading With Field Loss

A Study to Investigate the Safety of OpCT-001 in Adults Who Have Primary Photoreceptor Disease (CLARICO)

PAVE (Parallactic Visual-Field Enhancement) System for Treatment of Chronic Visual Field Loss Due to Stroke, Traumatic B…

All recent trials (100 shown)

Efficacy and Safety Trial of Sodium Valproate, in Paediatric and Adult Patients With Wolfram Syndrome

Oral N-acetylcysteine for Retinitis Pigmentosa

Implementing Artificial Intelligence to Prevent Vision Loss From Diabetes

Leveraging Artificial Intelligence to Prevent Vision Loss From Diabetes

Vision Screening in Hospitals for Older Adults Following a Fall

Brain Stimulation Effects on Orientation and Mobility Skills in Adults With Vision Impairment

AMX0035 in Adult Patients With Wolfram Syndrome

Post Marketing Study to Evaluate the Safety and Effectiveness of Brolucizumab in Patients With Diabetic Macular Edema.

Improve the Patients' Recovery With Family- Caregivers to End Delirium

Sight and Hearing Investigation Into Effects on Delirium

A Multicenter, Randomized Study in Participants With Diabetic Retinopathy Without Center-involved Diabetic Macular Edema…

Evaluating the Safety of BONEBRIDGE Implants in Children Under Five Years Old: This Study Looks at Children Under Five W…

Genetic Analyses of Nonsyndromic and Syndromic Deafness in Pakistan

Comparison of Phacoemulsification and Corneal Damage Between FLACS and Standard Phaco With Two Handpieces

Safety and Efficacy of 0.75% Phentolamine Ophthalmic Solution in Subjects With Post-refractive Surgery Visual Disturbanc…

A Study Evaluating the Safety and Efficacy of ENV-101 (Taladegib) in Patients With Advanced Solid Tumors Harboring PTCH1…

Sensory Substitution and Brain Plasticity Following Vision Loss

Efficacy Study of GS010 for the Treatment of Vision Loss up to 6 Months From Onset in LHON Due to the ND4 Mutation

Efficacy Study of GS010 for Treatment of Vision Loss From 7 Months to 1 Year From Onset in LHON Due to the ND4 Mutation…

Role of UC-MSC and CM to Inhibit Vision Loss in Retinitis Pigmentosa Phase I/II