Severe Chronic Periodontitis

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Severe Chronic Periodontitis trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 3 trials

RecruitingPhase 2

NCT07293962

3-Month Clinical Trial of Liquid S-PRF in Periodontal Debridement for Periodontitis Stages II-IV

What is the purpose of this study? This study is to investigate the effect of a processed blood product in healing after treatment for gum disease. In addition…

Malaysia14 participantsStarted 2024-04-01

Treatment: Normal saline irrigation, Platelet rich fibrin

RecruitingNot Applicable

NCT06893107

Study on Treatment Results and Bone Changes After Replanting Severely Affected Teeth - A Before-and-After Study.

This research aims to evaluate the effectiveness of intentional replantation (IR) as a treatment for single-rooted teeth diagnosed as hopeless due to true perio…

United Arab Emirates45 participantsStarted 2024-03-25

Treatment: Intentional Replantation

RecruitingPhase 3

NCT05902208

Contribution of an Antiviral Drug (Valaciclovir) in the Treatment of Generalized Periodontitis (Stage III or IV and Grad…

Periodontitis is an inflammatory pathology that destroys periodontitis and causes tooth loosening. Its high incidence, combined with very high oral and systemic…

France142 participantsStarted 2024-02-05

Treatment: Antiviral treatment with conventional non-surgical treatment, Placebo with conventional non-surgical treatment

All recent trials (27 shown)

CompletedNot Applicable

NCT07503041

Effect of Non-surgical Treatment of Periodontitis Patients Focusing on Inflammatory Mediators in Gingival Crevicular Flu…

This study investigates inflammatory biomarkers in gingival crevicular fluid (GCF) from smokers and non-smokers with severe periodontitis, before and during non…

Norway30 participantsStarted 2016-01-08

Treatment: Collecting fluid for biomarker analyses, Hygiene instruction, tooth cleaning, plaque removal

CompletedNot Applicable

NCT05698823

Regular Home-use of Dual-light Photodynamic Therapy in the Management of Chronic Stage III-IV Periodontitis

This study is designed to determine the efficacy of the Lumoral method in chronic periodontitis with a targeted group of stage III and IV periodontitis. Improv…

Lithuania56 participantsStarted 2023-06-06

Treatment: Lumoral Treatment

Severe Chronic Periodontitis

Trial phase breakdown

Trial status

Actively recruiting — 3 trials

3-Month Clinical Trial of Liquid S-PRF in Periodontal Debridement for Periodontitis Stages II-IV

Study on Treatment Results and Bone Changes After Replanting Severely Affected Teeth - A Before-and-After Study.

Contribution of an Antiviral Drug (Valaciclovir) in the Treatment of Generalized Periodontitis (Stage III or IV and Grad…

All recent trials (27 shown)

Effect of Non-surgical Treatment of Periodontitis Patients Focusing on Inflammatory Mediators in Gingival Crevicular Flu…

Regular Home-use of Dual-light Photodynamic Therapy in the Management of Chronic Stage III-IV Periodontitis

Trial phase breakdown

Trial status

Actively recruiting — 3 trials

3-Month Clinical Trial of Liquid S-PRF in Periodontal Debridement for Periodontitis Stages II-IV

Study on Treatment Results and Bone Changes After Replanting Severely Affected Teeth - A Before-and-After Study.

Contribution of an Antiviral Drug (Valaciclovir) in the Treatment of Generalized Periodontitis (Stage III or IV and Grad…

All recent trials (27 shown)

Effect of Non-surgical Treatment of Periodontitis Patients Focusing on Inflammatory Mediators in Gingival Crevicular Flu…

Regular Home-use of Dual-light Photodynamic Therapy in the Management of Chronic Stage III-IV Periodontitis

Evaluation of Macrophage Inflammatory Protein-1α as a Periodontal Disease Biomarker

Treatment of Periodontitis With Er:YAG Laser

Effect of Azithromycin on Failure Proportion of Severe Periodontitis Non-surgical Treatment

Chronic Presence of Epstein Barr Virus in Sulcular and Junctional Epithelial Tissue From Gingiva is Associated With Seve…

Flurbiprofen Versus Aloe Vera Gel in the Treatment of Chronic Periodontitis in Smoking Patients.

Hyaluronic Acid Versus Red Injectable Platelet Rich Fibrin in Treatment of Periodontitis

Effects of Non-surgical Periodontal Therapy on Severe Periodontitis and Hyperlipidemia

Scaling and Root Planning With Localized Delivery of Autogenous Growth Factors- Platelet Rich Fibrin (PRF)

Oral Health and Severe COPD

Clinical Evaluation of Laser Therapy Used as an Adjunct to Non-Surgical Treatment of Gum Disease

Treatment of Chronic Medium-severe Periodontitis With Mesenchymal Stem Cells Predifferentiated in Osteogenic Direction

Non-surgical Peridontal Treatment on Cardiovascular Risk Markers

Clinical and Radiograhic Evaluation of NIPSA With and Without Allograft Plus Platelet Rich Fibrin in the Treatment of In…

Full-mouth Treatment Approaches in Severe Chronic Periodontitis.

Effects of Vitamin D on Moderate to Severe Periodontitis

Evaluation of the Efficacy of 0.8% Hyaluronic Acid Gel

Quantification of Proteomes: L-plastin , Lipocalin and Adiponectin in Chronic Periodontitis and Diabetic Subjects

Periodontal Therapy in Thalassemia Major Patients