Regular Home-use of Dual-light Photodynamic Therapy in the Management of Chronic Stage III-IV Periodontitis

Inclusion Criteria: * Periodontal disease stage III-IV, according to criteria the American Academy of Periodontology (AAP) with at least 3 mm interdental clinical attachment level (CAL) in the site of greatest loss. * ≥ 18 years old * Presence of ≥20 teeth, including implants * Agreement to participate in the study and to sign a written consent form * Able to co-operate with the treatment protocol and avoid any other oral hygiene measures outside of the study protocol Exclusion Criteria: * Grade A or C periodontitis * Presence of any physical limitation or restriction that might restrict Lumoral use * Pregnancy or lactation * Active smoking * Medicated diabetes mellitus (DM) * Any systemic disease (e.g., wound healing dysfunctions) that could alter the progression of periodontal disease * Use of antibiotics within 4 weeks week prior study * Periodontal treatment within 3 months prior study * Removable major prosthesis or major orthodontic appliance * A need for a hopeless teeth extraction, or open cavities in need for immediate endodontic treatment