Evaluation of the Efficacy of 0.8% Hyaluronic Acid Gel

Inclusion Criteria: * Patients should be systemically healthy with moderate to severe chronic periodontitis of more than 4 mm probing depth in at least two sites in different quadrants. * Patient should exhibit no known allergies * Participants should have the ability to attend the hospital regular intervals. Exclusion Criteria: * pregnancy * nursing * hypertension * patient with chronic diseases such as diabetes mellitus or rheumatoid arthritis. -Participants should not be under antibiotics and\\or had receive any periodontal therapy for the last 6 months. * Participants should not taking drugs that could affect the state of the gingival tissues. * Participants must not be undergoing orthodontic therapy, caries free * Participants must not be using any other supplemental plaque control measures like mouthwashes. * Participants should not have the habit of taking alcohol, smoking or chewing tobacco and do not suffer from any systemic disease.