Ocular Surface Symptom

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Ocular Surface Symptom trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 3 trials

RecruitingNot Applicable

NCT07537426

The Efficacy of Intradermal Acupuncture for Ocular Surface Diseases After Intractable Facial Paralysis

The purpose of this study is to explore the clinical efficacy of intradermal acupuncture in the treatment of ocular surface diseases after Intractable Facial Pa…

China78 participantsStarted 2026-04-01

Treatment: Intradermal acupuncture treatment, Sham intradermal acupuncture

RecruitingPhase 4

NCT07502378

Effect of Acoltremon Ophthalmic Solution 0.003% on Signs and Symptoms of Ocular Surface Disease in Stage I Neurotrophic…

STUDY OBJECTIVE To assess if acoltremon 0.003% improves tear production in patients with Stage 1 Neurotrophic Keratopathy.

United States50 participantsStarted 2026-03-27

Treatment: Patients will receive topical Acoltremon 0.003% ophthalmic solution BID in both eyes over an 8 week period., Alternative would be patient exiting the trial and starting on tears or other standard of care.

RecruitingNot Applicable

NCT05039684

Inflammatory Biomarkers in Ocular Surface in Primary Open Angle Glaucoma or Ocular Hypertension Under Topical Prostaglan…

Glaucoma is a chronic optic neuropathy whose main modifiable risk factor is an abnormally elevated intraocular pressure. The aim of glaucoma treatment is to slo…

Spain40 participantsStarted 2021-10-01

All recent trials (38 shown)

Active — Not RecruitingNot Applicable

NCT07385495

OJO-miR: microRNA Expression in Allergic Conjunctivitis.

Allergic conjunctivitis (AC) causes inflammation of the conjunctiva in response to environmental allergens, affecting a significant percentage of the world popu…

Mexico40 participantsStarted 2026-01-05

SuspendedNot Applicable

NCT04838223

Neurosensory Abnormalities in SymptomAtic Ocular Surface Patients (NASA)

This study is designed to measure how common nerve abnormalities are within a group of patients who feel discomfort within their eyes.

United States1,000 participantsStarted 2021-07-02

Treatment: Hyperosmolar Response, Proparacaine Challenge Test

Ocular Surface Symptom

Trial phase breakdown

Trial status

Actively recruiting — 3 trials

The Efficacy of Intradermal Acupuncture for Ocular Surface Diseases After Intractable Facial Paralysis

Effect of Acoltremon Ophthalmic Solution 0.003% on Signs and Symptoms of Ocular Surface Disease in Stage I Neurotrophic…

Inflammatory Biomarkers in Ocular Surface in Primary Open Angle Glaucoma or Ocular Hypertension Under Topical Prostaglan…

All recent trials (38 shown)

OJO-miR: microRNA Expression in Allergic Conjunctivitis.

Neurosensory Abnormalities in SymptomAtic Ocular Surface Patients (NASA)

Trial phase breakdown

Trial status

Actively recruiting — 3 trials

The Efficacy of Intradermal Acupuncture for Ocular Surface Diseases After Intractable Facial Paralysis

Effect of Acoltremon Ophthalmic Solution 0.003% on Signs and Symptoms of Ocular Surface Disease in Stage I Neurotrophic…

Inflammatory Biomarkers in Ocular Surface in Primary Open Angle Glaucoma or Ocular Hypertension Under Topical Prostaglan…

All recent trials (38 shown)

OJO-miR: microRNA Expression in Allergic Conjunctivitis.

Neurosensory Abnormalities in SymptomAtic Ocular Surface Patients (NASA)

A Clinical Study to Determine What Effect the EyeCool Treatment Has on the Eye's Surface Anatomy and Inflammation Respon…

Potential Role of Ocular Surface Microbiome in Dry Eye: Microbial Interactions and Symptom Alleviation

Azithromycin for Meibomian Gland Disease

Dietary Supplementation on Tear Secretion and Inflammation in DES

Cool vs Room-temperature Artificial Tears

Efficacy and Safety of Oral Probiotics on Ocular Symptoms and Gut Microbiome of Children with Vernal Keratoconjunctiviti…

Limbal Stem Cell Deficiency (LSCD) Treatment With Cultivated Stem Cell (CALEC) Graft

Effect of Povidone-iodine 5% Vs 1% on the Ocular Surface in Intravitreal Injections of Anti-VEGF

Study of Efficacy and Safety of SAF312 Eye Drops in Subjects With Post-operative Corneal Induced Chronic Pain (CICP)

Efficacy and Safety of Topical Cyclosporine 0.05% and Lifitgrast on the Ocular Surface Symptom After Photorefractive Ker…

MicroPulse Transscleral Laser Therapy and Its Short-term Impact on Ocular Surface

Pilot Study to Investigate the Feasibility, Reliability and Efficacy of Utilizing OCT to Automate PROSE Fitting

Eye Surface Properties After Using Dexamethasone Drops With and Without Preservatives in Patients After Cataract Surgery

Dry Eye OmniLenz Application of Omnigen Research Study

Optic Nerve Diameter and Intraocular Pressure Changes in Patients Undergoing Vitrectomy Under General Anesthesia

Effect on Ocular Surface Symptoms of Online Education

Survey: Evaluation of Ocular Surface Disease Symptoms and Patient Satisfaction With Thealoz® Duo After 84 Days of Daily…

Efficacy and Safety of PRO-155 on Inflammation of the Conjunctival Surface in Subjects With Grade I-III Pterygium vs Pla…