CompletedPhase 4

Cool vs Room-temperature Artificial Tears

United States124 participantsStarted 2022-03-01

Plain-language summary

Background and Objective: To evaluate the efficacy of cooled versus room temperature artificial tears in reducing post intravitreal injection (IVI) ocular discomfort. Patients and Methods: Patients receiving IVI were randomized to either cooled or room temperature tears intervention groups. Both groups rated their ocular discomfort following IVI before intervention and again after administration of cooled or room temperature tears.

Who can participate

Age range18 Years – 105 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients were eligible if they were receiving standard intravitreal injections for their exudative age-related macular degeneration, cystoid macular edema, diabetic macular edema, proliferative diabetic retinopathy, retinal vein occlusion with macular edema, or retinal neovascularization. Exclusion Criteria: * Inability or lack of willingness to participate in the study * Active ocular infection including infectious uveitis * First time receiving intravitreal injection * Those who reported never having ocular discomfort following intravitreal injections on the pre-injection questionnaire * Less than 18 years of age

What they're measuring

The Efficacy of Cooled Versus Room Temperature Artificial Tears in Reducing Post Intravitreal Injection Ocular Discomfort as Measured by Pain Scale Survey.

Timeframe: with 72 hours of the intervention

Trial details

NCT IDNCT05832996

SponsorUniversity of Iowa

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-07-01

Results submitted2023-06-05

View on ClinicalTrials.gov More Diabetic Retinopathy With Macular Edema of Both Eyes (Diagnosis) trials