Functional Disorder

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Functional Disorder trials you may qualify for

100

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 42 trials

RecruitingPhase 3

NCT06709014

A Double-blind Dual Study Assessing Safety and Efficacy of Buntanetap in Participants With Early AD

The goal of this clinical trial is to learn if buntanetap/Posiphen works to treat early Alzheimer's disease in adults aged 55-85. It will also learn about the s…

United States760 participantsStarted 2025-02-04

Treatment: buntanetap/posiphen, Placebo

RecruitingNot Applicable

NCT05538910

Defining Neurobiological Links Between Substance Use and Mental Illness

Background: Nicotine dependence leads to about 480,000 deaths every year in the United States. People with major depressive disorder (MDD) are twice as likely…

United States620 participantsStarted 2023-02-02

Treatment: Placebo Nicotine Patch, Nicotine Patch

RecruitingNot Applicable

NCT07578831

Comparative Effects of Kendall and Feldenkrais Exercise in Upper Crossed Syndrome

Upper Cross Syndrome (UCS) is a prevalent musculoskeletal disorder characterized by muscular imbalances and postural dysfunction. Kendall Method and Feldenkrais…

Pakistan72 participantsStarted 2026-01-15

Treatment: Kendall Exercise Method (KM), Feldenkrais Exercise Method (FM)

RecruitingNot Applicable

NCT06191640

Sinus Disease in Young Children With Cystic Fibrosis

This is a prospective, observational study examining the impact of highly effective cystic fibrosis transmembrane conductance regulator (CFTR) modulators on chr…

United States80 participantsStarted 2023-04-12

Treatment: Ivacaftor or elexacaftor/tezacaftor/ivacaftor

RecruitingPhase 1/2

NCT05972564

The Effect of SGLT2 Inhibition on Adipose Inflammation and Endothelial Function

Obesity is associated with increased cardiometabolic disease risk due, in part, to heightened chronic inflammation arising from adipose tissue. There are no cur…

United States74 participantsStarted 2023-09-06

Treatment: Empagliflozin 25 MG, Placebo

RecruitingPhase 1

NCT07169630

PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)

Background: About 5 million adults in the United States have age-related brain disorders. These include Alzheimer disease (AD), mild cognitive impairment (MCI)…

United States90 participantsStarted 2026-05-14

Treatment: 18F-PF974, 18F-florbetaben

All recent trials (100 shown)

Not Yet RecruitingNot Applicable

NCT07578792

Standard vs Dual-Task Hand-Arm Bimanual Training in Post-Stroke Patients

This study aims to compare the effects of standard and dual-task-oriented hand-arm bimanual intensive training on cognitive performance, upper limb function, an…

Pakistan20 participantsStarted 2026-06-01

Treatment: Standard HABIT, Dual-Task-Oriented HABIT

CompletedNot Applicable

NCT06173193

Effects of Multicomponent Exercise on Subchondral Bone and Cartilage in Postmenopausal Women With Knee Osteoarthritis

Today, osteoarthritis (OA) is considered a whole-organ disease that is amenable to prevention and treatment in the early stages. Information on the articular ca…

Finland103 participantsStarted 2023-06-01

Treatment: Multicomponent exercise regimen, Standard rehabilitative management

Functional Disorder

Trial phase breakdown

Trial status

Actively recruiting — 42 trials

A Double-blind Dual Study Assessing Safety and Efficacy of Buntanetap in Participants With Early AD

Defining Neurobiological Links Between Substance Use and Mental Illness

Comparative Effects of Kendall and Feldenkrais Exercise in Upper Crossed Syndrome

Sinus Disease in Young Children With Cystic Fibrosis

The Effect of SGLT2 Inhibition on Adipose Inflammation and Endothelial Function

PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)

All recent trials (100 shown)

Standard vs Dual-Task Hand-Arm Bimanual Training in Post-Stroke Patients

Effects of Multicomponent Exercise on Subchondral Bone and Cartilage in Postmenopausal Women With Knee Osteoarthritis

Trial phase breakdown

Trial status

Actively recruiting — 42 trials

A Double-blind Dual Study Assessing Safety and Efficacy of Buntanetap in Participants With Early AD

Defining Neurobiological Links Between Substance Use and Mental Illness

Comparative Effects of Kendall and Feldenkrais Exercise in Upper Crossed Syndrome

Sinus Disease in Young Children With Cystic Fibrosis

The Effect of SGLT2 Inhibition on Adipose Inflammation and Endothelial Function

PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)

All recent trials (100 shown)

Standard vs Dual-Task Hand-Arm Bimanual Training in Post-Stroke Patients

Effects of Multicomponent Exercise on Subchondral Bone and Cartilage in Postmenopausal Women With Knee Osteoarthritis

PASCAL Precision-GDMT Registry

Unilateral and Bilateral taVNS in Fibromyalgia

Combined Effects of Tactile Kinesthetic Stimulation With Neural Mobilization in Stroke Patients

Impact of Oral Nutritional Supplements on Patients Undergoing Haematopoietic Stem Cell Transplantation

Effect of Digestive Enzymes as Add on Therapy on Patients With Functional Dyspepsia.

Cognitive Behavioral Therapy for Functional Dyspepsia (Epigastric Pain Syndrome and Postprandial Distress Syndrome Subty…

Efficacy of Intracavernosal Xeomin With Tadalafil for Mild-Moderate Erectile Dysfunction

Mitochondrial dysfUnction: a Key Player in Doxorubicin-induced Skeletal and Cardiac muscLE Damage

Innate Immune Immunoparalysis and Ventilator-Associated Pneumonia in Critically Ill Elderly Patients

Comparative Effects of Somatosensory Stimulation and Task Based Mirror Therapy in Post Stroke Patients

Resveratrol for Endothelial Dysfunction and Metabolic Control in Type 2 Diabetes

The Effect of tDCS Combined With TMS on Cognitive Impairment and Motor Function After Stroke

TearCare in Young Adults

Prevalence and Development of Liver Dysfunction in Hematopoietic Stem Cell Transplant

Evaluating the Relationship Between Function and Structure Using Data From a GA Natural History Cohort

A Study of Donanemab (LY3002813) in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 5)

eMPower Mechanisms

Air Stacking-Assisted Diaphragmatic Breathing in Stroke