Cocaine Abuse and Dependence

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Cocaine Abuse and Dependence trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 2 trials

RecruitingPhase 4

NCT07313371

Efficacy of Clonidine in Reducing Craving in Inpatients With Cocaine and Crack Use Disorder

This is a single-center, randomized intervention study in a volunteer population of patients with cocaine/crack use disorder to evaluate the pharmacological tre…

Brazil36 participantsStarted 2026-01-28

Treatment: clonidine, clonazepam 0,25 mg

RecruitingPhase 2

NCT06434818

Enhanced Digital-Chemosensory-Based Olfactory Training for Remote Management of Substance Use Disorders

The overarching goal of this study phase, Phase II component is to implement Enhanced Digital-Chemosensory-Based Olfactory Training for Remote Management of Sub…

United States300 participantsStarted 2023-07-07

Treatment: EDITOR (CBOT with olfactory stimulants, OFC tasks & remote monitoring of treatment compliance), CBOT with olfactory stimulants & OFC tasks

All recent trials (42 shown)

CompletedPhase 4

NCT00232336

Quetiapine for Cocaine Use and Cravings

The purpose of this study was to collect pilot data on whether quetiapine may be effective in the reduction of cocaine use and cravings in cocaine dependent ind…

United States42 participantsStarted 2003-10

Treatment: quetiapine

CompletedPhase 1

NCT02563769

Clavulanic Acid (CLAV) and Cocaine Interaction Safety Study

The main purpose of this study is to determine if it is safe to use the study drug, clavulanic acid, in combination with cocaine. In this study, subjects will r…

United States10 participantsStarted 2016-10-24

Treatment: Clavulanic acid, Intravenous cocaine

Cocaine Abuse and Dependence

Trial phase breakdown

Trial status

Actively recruiting — 2 trials

Efficacy of Clonidine in Reducing Craving in Inpatients With Cocaine and Crack Use Disorder

Enhanced Digital-Chemosensory-Based Olfactory Training for Remote Management of Substance Use Disorders

All recent trials (42 shown)

Quetiapine for Cocaine Use and Cravings

Clavulanic Acid (CLAV) and Cocaine Interaction Safety Study

Trial phase breakdown

Trial status

Actively recruiting — 2 trials

Efficacy of Clonidine in Reducing Craving in Inpatients With Cocaine and Crack Use Disorder

Enhanced Digital-Chemosensory-Based Olfactory Training for Remote Management of Substance Use Disorders

All recent trials (42 shown)

Quetiapine for Cocaine Use and Cravings

Clavulanic Acid (CLAV) and Cocaine Interaction Safety Study

Effect of rTMS on Neurotrophines Levels in CUD

Study to Investigate Whether AFQ056 Reduces Cocaine Use in Patients Diagnosed With Cocaine Use Disorder (CUD)

Progesterone for the Treatment of Cocaine Dependence - 1

Modafinil and Naltrexone to Reduce Cocaine and Alcohol Dependence

Methylphenidate Treatment for Cocaine Abuse and ADHD - 1

Enhanced and Attendance-based Prize CM in Community Settings

Clinical Neurobiology of Serotonin and Addiction

Pharmacotherapy Dosing Regimen in Cocaine and Opiate Dependent Individuals - 8

Brain Glutamate Receptors and Cocaine Dependence

Effect of Clonidine on Responses to Imagery Scripts

Real Time Assessment of Drug Craving, Use, and Abstinence During Outpatient: A Development and Feasibility Study

Effects of N-acetylcysteine on Brain Chemistry and Behavior in Cocaine Abusers (NAC)

VIVITROL as a Treatment for Cocaine and Alcohol Dependence

Brain Function and Structure in Cocaine Dependence

Treatment of Cocaine Dependence: Comparison of Three Doses of Dextro-Amphetamine Sulfate and Placebo

Employment-based Reinforcement of Naltrexone Ingestion and Abstinence

Risk Perception in Drug-Dependent Adults With and Without Schizophrenia

Medications for Stopping Cocaine Dependence and Preventing Relapse