CompletedPhase 1

Methylphenidate Treatment for Cocaine Abuse and ADHD - 1

United States124 participantsStarted 1998-04

Plain-language summary

Many cocaine dependent individuals are also diagnosed with Attention Deficit Hyperactivity Disorder (ADHD). Methylphenidate (Ritalin) is currently approved to treat individuals diagnosed with ADHD. The purpose of this study is to determine the effectiveness of methylphenidate in treating ADHD symptoms in cocaine dependent individuals.

Who can participate

Age range18 Years – 60 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Meets DSM-IV criteria for cocaine dependence * Meets DSM-IV criteria for persistent adult Attention Deficit Hyperactive Disorder Exclusion Criteria: * Meets DSM-IV criteria for current psychiatric disorders (other than ADHD or substance abuse) that requires a psychiatric intervention * Physiologically dependent on sedatives or alcohol, to the extent that medical attention is required during periods of abstinence or significant reduction in the amount of use * Exhibits suicidal or homicidal behavior within the two years prior to enrollment * Currently taking prescription psychotropic medication * Unstable medical condition (e.g., uncontrolled diabetes) that would make participation in the study hazardous * Known sensitivity to methylphenidate * Pregnant or breastfeeding

What they're measuring

ADHD symptom severity based on the ADHD rating scale score

Timeframe: measured weekly for the 14 weeks of the trial or length of study participation

self reported cocaine use

Timeframe: recorded daily for the 14 weeks of the trial or the length of participation

Trial details

NCT IDNCT00136734

SponsorNew York State Psychiatric Institute

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2004-03

View on ClinicalTrials.gov More Attention Deficit Disorder With Hyperactivity trials