Azoospermia, Nonobstructive

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Azoospermia, Nonobstructive trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 4 trials

RecruitingNot Applicable

NCT07357701

Identifying Genome Variants in Non-Obstructive Azoospermia (NOA) or Primary Ovarian Insufficiency (POI)

Background: Infertility affects 1 in 6 people. Often, the causes of infertility are unknown. Treatments are successful in only about 50% of cases. Infertility…

United States500 participantsStarted 2026-03-11

RecruitingNot Applicable

NCT05479474

Platelet Rich Plasma Testis Treatment for Infertile Men

Investigate the effect of intratesticular injection of autologous platelet rich plasma (PRP) on sperm retrieval rates and IVF outcomes in infertile men who alre…

United States10 participantsStarted 2023-01-18

Treatment: Platelet rich plasma

RecruitingPhase 1/2

NCT06869863

Study of Tolerability, Safety, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of the Medicinal Product Medi…

The study is open to patients with severe forms of male infertility (non-obstructive disorders of spermatogenesis, including azoospermia). The Phase I/II clini…

Russia80 participantsStarted 2024-11-26

Treatment: Medicinal product MediReg® (Human Mesenchymal Stromal Cell Secretome), lyophilizate for preparation of solution for injection in patients with severe spermatogenesis disorders, Clostilbegit (clomiphene) 50 mg 1 tablet x 1 p a day - 3 months, Triovit - 1 tablet x 1 p a day - 3 months, Folic acid - 1 tablet x 1 p a day - 3 months.

RecruitingNot Applicable

NCT06181851

2015-Metabolomics&Microbiome-infertility

The study aims to carry out a translational analysis of the microbiome and metabolomics in patients suffering from non-obstructive azoospermia, with the aim of…

Italy45 participantsStarted 2016-06-01

Treatment: Analysis of microbiome and metabolomics

All recent trials (23 shown)

By InvitationPhase 2

NCT07481370

Isotretinoin vs hCG for Male Infertility Due to Low or Absent Sperm

This study compares two medical treatments to see how well they improve sperm production in men with infertility due to low sperm counts (oligospermia) or no sp…

United States100 participantsStarted 2026-04-13

Treatment: isotretinoin, Human chorionic gonadotrophin (hCG)

CompletedNot Applicable

NCT07415928

Inhibin B/FSH Ratio as a Predictor of Testicular Pathology in NOA

This retrospective observational study evaluated the diagnostic and predictive value of serum Inhibin B (INHB), follicle-stimulating hormone (FSH), and the INHB…

Turkey (Türkiye)73 participantsStarted 2026-01-10

Azoospermia, Nonobstructive

Trial phase breakdown

Trial status

Actively recruiting — 4 trials

Identifying Genome Variants in Non-Obstructive Azoospermia (NOA) or Primary Ovarian Insufficiency (POI)

Platelet Rich Plasma Testis Treatment for Infertile Men

Study of Tolerability, Safety, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of the Medicinal Product Medi…

2015-Metabolomics&Microbiome-infertility

All recent trials (23 shown)

Isotretinoin vs hCG for Male Infertility Due to Low or Absent Sperm

Inhibin B/FSH Ratio as a Predictor of Testicular Pathology in NOA

Trial phase breakdown

Trial status

Actively recruiting — 4 trials

Identifying Genome Variants in Non-Obstructive Azoospermia (NOA) or Primary Ovarian Insufficiency (POI)

Platelet Rich Plasma Testis Treatment for Infertile Men

Study of Tolerability, Safety, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of the Medicinal Product Medi…

2015-Metabolomics&Microbiome-infertility

All recent trials (23 shown)

Isotretinoin vs hCG for Male Infertility Due to Low or Absent Sperm

Inhibin B/FSH Ratio as a Predictor of Testicular Pathology in NOA

Autologous Transplantation of Human Cryopreserved Testis Tissue

Retrieval of Sperm From Men With Azoospermia Using Ultrasound-guided Rete Testis Aspiration

Timing of Oocyte Retrieval and Micro Testicular Sperm Extraction

Interest of Clomiphene Citrate in Patients With Non-obstructive Azoospermia on the Quantity of Sperm Cells

Management of Non Obstructive Azoospermia in Men

TeSE (Testicular Sperm Extraction) in Azoospermic Patients: m-TeSE vs. l-TeSE

Machine Learning Based-Personalized Prediction of Sperm Retrieval Success Rate

The Potential of Sperm Retrieved by Micro-TESE to Fertilize Vitrified/Warmed Oocytes

Hormonal Stimulation of Spermatogenesis

Effect of Age on Sperm Recovery of Microdissection Testicular Sperm Extraction in Nonobstructive Azoospermia Patients

Seminal Level of Clusterin Before Testicular Sperm Extraction

The Effects of Intratesticular PRP Injection in Men With Azoospermia or Cryptozoospermia

Seminal TEX101 as a Predictor of Recovery of Spermatogenesis in Azoospermic Men With Palpable Varicocele

TESE and Non Obstructive Azoospermia

Effect of Letrozole on Seminal Parameters in Men With Non Obstructive Azoospermia and Severe Oligozoospermia.

GnRHa Combined With hCG and hMG for Treatment of Patients With Non-obstructive Azoospermia

FSH Treatment for Non-obstructive Azoospermic Patients