CompletedNot Applicable

TeSE (Testicular Sperm Extraction) in Azoospermic Patients: m-TeSE vs. l-TeSE

Italy42 participantsStarted 2022-03-01

Plain-language summary

The aim of the study is to compare surgical outcomes (intra and post-operative complications) and sperm retrieval rates between conventional microsurgical-assisted testicular sperm extraction (m-TeSE - Group A) and testicular sperm extraction performed with surgical loupes (l-TeSE - Group B) in adult males with non-obstructive azoospermia.

Who can participate

Age range18 Years

SexMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adult males * Diagnosis of non obstructive azoospermia who required m-TeSE. Exclusion Criteria: * Absence of signed written informed consent * Age \< 18 years * Obstructive azoospermia * Genetic anomalies (e.g., Klinefelter syndrome, Kallmann syndrome, Y chromosome microdeletions, CFTR mutations) * Previous testicular biopsies/surgical sperm retrieval * Personal history of malignant testicular tumor * Unilateral cryptorchidism * Varicocele * Previous chemotherapy/radiotherapy treatments * Monorchidism

What they're measuring

Positive sperm retrieval

Timeframe: immediately after the surgery

Histology

Timeframe: immediately after the surgery

Johnsen score

Timeframe: immediately after the surgery

Sperm vials stored

Timeframe: immediately after the surgery

Trial details

NCT IDNCT06702397

SponsorA.O.U. Città della Salute e della Scienza

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-04-30

View on ClinicalTrials.gov More Azoospermia, Nonobstructive trials