Aspirin-exacerbated Respiratory Disease

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Aspirin-exacerbated Respiratory Disease trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

RecruitingNot Applicable

NCT04538937

Prospective Registry of Eosinophilia With Respiratory Manifestations With Translational Research Identifying and Charact…

Introduction: The etiology and therapy of eosinophilic lung diseases are still poorly understood. For individual forms of disease, such as eosinophilic asthma o…

Austria300 participantsStarted 2020-02-26

Treatment: no intervention

All recent trials (31 shown)

CompletedPhase 2

NCT05031455

Mechanisms of Dupilumab in AERD

Aspirin-Exacerbated Respiratory Disease (AERD), although uncommon in the general population, is an important phenotype of severe asthma and nasal polyposis wher…

United States16 participantsStarted 2024-03-25

Treatment: Aspirin Challenge

CompletedPhase 4

NCT04823585

Aggravated Airway Inflammation: Research on Biological Treatment (Mepolizumab)

Primary objective: to investigate the efficacy of Mepolizumab 100 milligram (mg) every month compared to placebo in reducing validated Sinonasal Outcome Test -…

Finland95 participantsStarted 2021-08-12

Treatment: Mepolizumab, Placebo

Aspirin-exacerbated Respiratory Disease

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

Prospective Registry of Eosinophilia With Respiratory Manifestations With Translational Research Identifying and Charact…

All recent trials (31 shown)

Mechanisms of Dupilumab in AERD

Aggravated Airway Inflammation: Research on Biological Treatment (Mepolizumab)

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

Prospective Registry of Eosinophilia With Respiratory Manifestations With Translational Research Identifying and Charact…

All recent trials (31 shown)

Mechanisms of Dupilumab in AERD

Aggravated Airway Inflammation: Research on Biological Treatment (Mepolizumab)

Role of IL-5R Signaling in Non-eosinophil Upper Airway Cells in CRSwNP

Mechanisms of Benefit of IL4RA Inhibition in Aspirin-Exacerbated Respiratory Disease

Long-term Effect of Dupilumab in N-ERD

Aggravated Airway Inflammation: Research on Genomics and Optimal Operative Treatment (AirGOs Operative)

Effect of Celecoxib on Postoperative Analgesia and Disease Severity in AERD Patients with CRS

Oral Ifetroban to Treat Aspirin Exacerbated Respiratory Disease (AERD)

Therapeutic Control of Aspirin-Exacerbated Respiratory Disease With Ifetroban

Long-term Aspirin Therapy as a Predictor of Decreased Susceptibility to SARS-CoV-2 Infection in Aspirin-Exacerbated Resp…

Diagnosis of Aspirin Hypersensitivity in Aspirin Exacerbated Respiratory Disease

Role of Inflammatory Mediators in AERD

Effect of Dupilumab on Aspirin Intolerance

Characteristics of Patients Diagnosed With NSAID Sensitivity in Thailand

Genetics and Genomics of Aspirin Exacerbated Respiratory Disease (AERD)

Characterisation of the Nasal Microbiome in Patients With N-ERD

Effect of Dietary Salicylate in Aspirin Exacerbated Respiratory Disease

Therapeutic Utility of Xolair in Patients Undergoing Aspirin Desensitization

Dupilumab for Aspirin-exacerbated Respiratory Disease

Characterisation of Nasal Polyps in Patients With and Without Aspirin-exacerbated Respiratory Disease