All-cause Mortality

Clinical trial pipeline · Data from ClinicalTrials.gov

See which All-cause Mortality trials you may qualify for

100

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 13 trials

RecruitingNot Applicable

NCT07563777

100-Year Human Aging Study

The 100-Year Human Aging Study is a prospective, pragmatic, observational trial enrolling participants across fixed and mobile clinical sites to undergo compreh…

United States10,000 participantsStarted 2025-02-09

Treatment: Comprehensive Multi-System Clinical Screening

RecruitingNot Applicable

NCT07209098

Propensity-Matched Study of Cardiac Contractility Modulation Therapy in Heart Failure

The purpose of this prospective, multi-center, propensity-matched coverage with evidence development (CED) study is to assess the impact of cardiac contractilit…

United States4,200 participantsStarted 2025-11-18

Treatment: Cardiac Contractility Modulation (CCM)

RecruitingNot Applicable

NCT05466825

The Global Cardiovascular Risk Consortium

The Global Cardiovascular Risk Consortium (GCVRC) brings together harmonized individual-level data from currently more than 2 million (anticipated: approximatel…

Germany3,000,000 participantsStarted 2019-09-20

RecruitingPhase 3

NCT06819592

PRophylaxis Against Early VENTilator-associated Infections in Acute Brain Injury

This research is about whether treatment with a commonly used antibiotic can prevent infections in airway and lungs and improves the chance of surviving, if it…

Australia3,300 participantsStarted 2025-10-30

Treatment: Ceftriaxone 2g diluted in >200ml 0.9%sodium chloride, Placebo comparator - no ceftriaxone

RecruitingNot Applicable

NCT02043691

Evaluation of the Cook Custom Aortic Endograft, the Zenith t-Branch Endovascular Graft, and Surgeon-Modified Endograft i…

This is a single-center study to evaluate the safety and effectiveness of three investigational devices, the Cook Custom Aortic Endograft, the Zenith t-Branch E…

United States410 participantsStarted 2014-06

Treatment: Cook Custom Aortic Endograft, Zenith t-Branch Endovascular Graft

RecruitingPhase 3

NCT06968559

Effect of Early Dexamethasone on Major Complications and All-cause Mortality in Severe Burns

Burns affect more than 11 million people worldwide each year. These injuries are responsible for severe morbidity resulting in a high societal burden and accoun…

France478 participantsStarted 2025-11-07

Treatment: Dexamethasone, Placebo

All recent trials (100 shown)

Active — Not RecruitingPhase 3

NCT06183931

Study of ALXN2220 Versus Placebo in Adults With ATTR-CM

The primary objective of this study is to access the efficacy of ALXN2220 in the treatment of adult participants with ATTR-CM by evaluating the difference betwe…

United States1,181 participantsStarted 2024-01-11

Treatment: ALXN2220, Placebo

Not Yet RecruitingNot Applicable

NCT07224659

Exercise and Mortality in Middle-Aged and Older Adults

This protocol is a retrospective study using the observational data of the the Prostate, Lung, Colorectal, and Ovarian (PLCO) screening trial with over 150,000…

United States19,000 participantsStarted 2026-04-01

Treatment: Control, Exercise

All-cause Mortality

Trial phase breakdown

Trial status

Actively recruiting — 13 trials

100-Year Human Aging Study

Propensity-Matched Study of Cardiac Contractility Modulation Therapy in Heart Failure

The Global Cardiovascular Risk Consortium

PRophylaxis Against Early VENTilator-associated Infections in Acute Brain Injury

Evaluation of the Cook Custom Aortic Endograft, the Zenith t-Branch Endovascular Graft, and Surgeon-Modified Endograft i…

Effect of Early Dexamethasone on Major Complications and All-cause Mortality in Severe Burns

All recent trials (100 shown)

Study of ALXN2220 Versus Placebo in Adults With ATTR-CM

Exercise and Mortality in Middle-Aged and Older Adults

Trial phase breakdown

Trial status

Actively recruiting — 13 trials

100-Year Human Aging Study

Propensity-Matched Study of Cardiac Contractility Modulation Therapy in Heart Failure

The Global Cardiovascular Risk Consortium

PRophylaxis Against Early VENTilator-associated Infections in Acute Brain Injury

Evaluation of the Cook Custom Aortic Endograft, the Zenith t-Branch Endovascular Graft, and Surgeon-Modified Endograft i…

Effect of Early Dexamethasone on Major Complications and All-cause Mortality in Severe Burns

All recent trials (100 shown)

Study of ALXN2220 Versus Placebo in Adults With ATTR-CM

Exercise and Mortality in Middle-Aged and Older Adults

Dynamic Magnesium Replacement Strategies and 28-Day Mortality in Non-Cardiac Critically Ill Patients With Hypomagnesemia…

Predicting Heart Failure Outcomes With Biomarkers and Imaging

Postoperative Frailty Trajectories and One-Year Mortality in Older Surgical Patients

The RENAL LIFECYCLE Trial: A RCT to Assess the Effect of Dapagliflozin on Renal and Cardiovascular Outcomes in Patients…

Ferric Citrate for the Prevention of Renal Failure in Adults With Advanced Chronic Kidney Disease

Care-HF CArdiac Resynchronization in Heart Failure

CARE-HF Long Term Follow-up

Perioperative Homocysteine and Postoperative Complications/All-Cause Mortality in Elderly Non-Cardiac Surgery Patients

Association of C-reactive Protein-albumin-lymphocyte Index (CALLY) With All-cause Mortality in Diabetic Patients

HiLo: Pragmatic Trial of Higher vs Lower Serum Phosphate Targets in Patients Undergoing Hemodialysis

Eating Away from Home and Risk of All-cause Mortality

The Effect of Probiotic Supplementation

Construction and Validation of a Prediction Model for All - Cause Mortality Within 30 Days After Surgery in Critically I…

All-cause and Diseases-specific Mortality of High-risk HPV Infection

Direct Oral Anticoagulants in Patients With Atrial Fibrillation (DOACs vs Warfarin)

Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors and Risk of Cardiovascular Events

Emulation of the Moderate Alcohol and Cardiovascular Health Trial (MACH15)

Clinical Study of Active Intervention in High-risk HFpEF Patients