Postoperative Frailty Trajectories and One-Year Mortality in Older Surgical Patients (NCT07322809) | Clinical Trial Compass
CompletedNot Applicable
Postoperative Frailty Trajectories and One-Year Mortality in Older Surgical Patients
China4,417 participantsStarted 2020-04-01
Plain-language summary
Frailty is a key predictor of adverse outcomes in older surgical patients, yet its longitudinal evolution and potentially reversible nature remain underexplored in perioperative settings. This study aimed to characterize postoperative frailty trajectories in older patients and to examine their association with one-year mortality, as well as factors influencing trajectory group.
Who can participate
Age range
65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Aged ≥65 years;
* Underwent elective non-cardiac, non-neurosurgical procedures;
* Completed standardized frailty assessments both preoperatively and postoperatively.
Exclusion Criteria:
* Severe dementia, language disorders, significant hearing or visual impairments, or coma;
* Cognitive function below the Mini-Mental State Examination (MMSE) thresholds (\<18 for illiterate individuals, \<21 for individuals with primary education, and \<25 for individuals with secondary education or higher);
* Surgery performed under local anesthesia or monitored anesthesia care;
* Surgical duration ≤30 minutes;
* Missing data on postoperative complications or one-year mortality required for this study;
* Incomplete frailty assessments at 1, 3, and 6 months after surgery.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This study tracked frailty levels in older surgical patients after an operation and followed them for a full year — based on what they found about frailty trajectories, does my current level of frailty put me at higher risk, and should that change how we approach my surgery?
2Since this trial has already been completed and was measuring one-year all-cause mortality, have the results been published, and can you walk me through what they found about which patients did better or worse over time?
3The study focused on how frailty changed in the period after surgery — is there a way to assess my frailty before my operation so we have a baseline to compare against afterward?
4Given that this research looked specifically at older surgical patients, do you think my age and health status match the kind of patients enrolled, and does that affect how relevant these findings are to my situation?
5If frailty after surgery is linked to worse one-year outcomes, are there steps we could take before or after my operation — like rehabilitation or closer follow-up — that might help reduce that risk for me?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
The primary outcome was one-year all-cause mortality.
Timeframe: At the one-year postoperative follow-up.