CompletedNot Applicable

Perioperative Homocysteine and Postoperative Complications/All-Cause Mortality in Elderly Non-Cardiac Surgery Patients

12,955 participantsStarted 2014-01-01

Plain-language summary

This study aims to explore the association between perioperative homocysteine (Hcy) levels and their pre-to-postoperative changes with postoperative complications and all-cause mortality in elderly patients undergoing non-cardiac surgery. Besides, the dynamic changes in Hcy levels may reflect metabolic shifts, highlighting their potential value in predicting adverse postoperative outcomes. These findings suggest that monitoring perioperative Hcy levels and their changes could help identify high-risk patients and inform postoperative management strategies.

Who can participate

Age range65 Years

SexALL

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Inclusion Criteria: * Hospitalized older (≥ 65 years) patients underwent non-cardiac surgery Exclusion Criteria: * 21227 patients without preoperative Hcy data * 957 patients undergoing neurosurgery * 3 patients call off the surgery for reasons * 164 patients with chronic kidney disease

What they're measuring

Acute kidney injury (AKI)

Timeframe: January 2014 - August 2019

Trial details

NCT IDNCT06959446

SponsorChinese PLA General Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2019-08-30

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