100-Year Human Aging Study (NCT07563777) | Clinical Trial Compass
RecruitingNot Applicable
100-Year Human Aging Study
United States1,000,000 participantsStarted 2025-02-09
Plain-language summary
The 100-Year Human Aging Study is a prospective, pragmatic, observational trial enrolling participants across fixed and mobile clinical sites to undergo comprehensive multi-system health screening and longitudinal follow-up until death. Participants are followed to determine whether measurements taken at enrollment and repeated across the lifespan - individually and in combination - predict all-cause mortality, cause-specific mortality, incident serious disease, and functional disability. The study is designed to generate the surrogate endpoint validation data that longevity medicine currently lacks.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age 18 years or older
* Willing and able to provide written informed consent, or enrollment with consent of a legally authorized representative
* Willing to participate in longitudinal follow-up
Exclusion Criteria:
* Age under 18 years
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This study is described as a 100-year aging study — does that mean it would follow me for the rest of my life, and what does that kind of long-term commitment actually look like in practice?
2Since this trial is listed as 'Phase NA' and is focused on observational outcomes like all-cause mortality rather than testing a specific treatment, does participating in it replace, delay, or run alongside any active treatment I might need for conditions like metabolic syndrome or cardiovascular disease?
3Given that the study tracks things like cognitive decline, frailty, and daily living activities over a very long period, what kinds of assessments or data collection would I be expected to participate in regularly, and how demanding might that be on my time and health?
4Because this study is measuring mortality and disease outcomes rather than offering a new therapy, what would my doctor say is the realistic personal benefit to me versus the contribution I'd be making to research on aging?
5If I have existing conditions like dementia risk factors or musculoskeletal issues that are listed as focus areas of this study, would my doctor consider those reasons I might be a good candidate to discuss enrolling, or are there reasons those same conditions could make participation complicated?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
All-Cause Mortality
Timeframe: From enrollment until death, assessed periodically, up to 100 years
2
Cause-Specific Mortality
Timeframe: From enrollment until death, assessed periodically, up to 100 years