The 100-Year Human Aging Study is a prospective, pragmatic, observational trial enrolling participants across fixed and mobile clinical sites to undergo comprehensive multi-system health screening and longitudinal follow-up until death. Participants are followed to determine whether measurements taken at enrollment and repeated across the lifespan - individually and in combination - predict all-cause mortality, cause-specific mortality, incident serious disease, and functional disability. The study is designed to generate the surrogate endpoint validation data that longevity medicine currently lacks.
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All-Cause Mortality
Timeframe: From enrollment until death, assessed periodically, up to 100 years
Cause-Specific Mortality
Timeframe: From enrollment until death, assessed periodically, up to 100 years