Vaginal Microbiome

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Vaginal Microbiome trials you may qualify for

100

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 32 trials

RecruitingNot Applicable

NCT07446205

Poi for Mama: a Pilot to Improve Maternal Microbiome and Gestational Diabetes Risk

This investigator-initiated, non-randomized pilot study evaluates the effect of daily consumption of fermented poi on the maternal microbiome and gestational di…

United States50 participantsStarted 2026-04-16

Treatment: Fermented Poi

RecruitingNot Applicable

NCT06873971

Er:YAG Laser Combined With Vaginal Estriol for Genitourinary Syndrome of Menopause

Chronic hypoestrogenism in postmenopausal women significantly impacts the urogenital epithelium, leading to Genitourinary Syndrome of Menopause (GSM) and increa…

Brazil60 participantsStarted 2025-12-10

Treatment: Topical estrogen therapy based on estriol (E3), Active Er:YAG Laser

RecruitingNot Applicable

NCT06646185

Improving Menstrual and VAginal Health for All

A three-period crossover trial will study the effects of short-term use of 3 menstrual products (menstrual pad, tampon, menstrual cup) on the bacterial composit…

Cameroon, Peru, Switzerland100 participantsStarted 2026-04-15

Treatment: Menstrual Pads, Menstrual Cups

RecruitingNot Applicable

NCT07471373

Pesticides and Infertility: Oxidative Stress Via Circulating Cell-free DNA and Gut/Genital Microbiome Signatures in Wome…

This project PestiEndoMicro aims to provide an innovative approach, studying endometriosis under the genital and gut microbiota scope. To realize this project,…

France160 participantsStarted 2026-02-27

Treatment: Circulating DNA analysis, Vaginal microbiota analysis

RecruitingNot Applicable

NCT06649201

Vulvovaginal Graft-versus-Host Disease: Diagnosis and Microbiome Evaluation

The goal of this observational study is to investigate the development of vulvovaginal graft-versus-host- disease (GVHD), an under-reported and under-recognized…

United States40 participantsStarted 2024-12-19

Treatment: Vulvovaginal Symptom Questionnaire, Vaginal Microbiome Evaluation

RecruitingNot Applicable

NCT05966649

Synbiotics in Patients at RIsk fOr Preterm Birth

Prematurity remains the main cause of death and serious health problems in new-borns. Besides the need for hospitalization and medical interventions in the firs…

Belgium402 participantsStarted 2023-03-16

Treatment: Synbiotics, Placebo

All recent trials (100 shown)

Active — Not RecruitingEarly Phase 1

NCT04930107

Vulvovaginal Candidiasis in Canadian Females

Vulvovaginal candidiasis (VVC; colloquially referred to as a 'yeast infection') is a prevalent mucosal infection caused by Candida spp. that affects \~75% of wo…

Canada120 participantsStarted 2021-12-07

Treatment: Fluconazole 150 mg, Boric Acid Supp,Vag

Not Yet RecruitingPhase 2/3

NCT07527572

Study to Evaluate Efficacy and Safety of Gyntima® Balance in Preventing Recurrences of Bacterial Vaginosis

The vagina is a dynamic muscular organ whose health relies on a Lactobacillus-dominant microbiota that maintains low pH and protects against infections. Bacteri…

Location not specified160 participantsStarted 2026-04-01

Treatment: Lactobacillus gasseri KABP®064 10e9 CFU/capsule, Placebo (maltodextrin)

Vaginal Microbiome

Trial phase breakdown

Trial status

Actively recruiting — 32 trials

Poi for Mama: a Pilot to Improve Maternal Microbiome and Gestational Diabetes Risk

Er:YAG Laser Combined With Vaginal Estriol for Genitourinary Syndrome of Menopause

Improving Menstrual and VAginal Health for All

Pesticides and Infertility: Oxidative Stress Via Circulating Cell-free DNA and Gut/Genital Microbiome Signatures in Wome…

Vulvovaginal Graft-versus-Host Disease: Diagnosis and Microbiome Evaluation

Synbiotics in Patients at RIsk fOr Preterm Birth

All recent trials (100 shown)

Vulvovaginal Candidiasis in Canadian Females

Study to Evaluate Efficacy and Safety of Gyntima® Balance in Preventing Recurrences of Bacterial Vaginosis

Trial phase breakdown

Trial status

Actively recruiting — 32 trials

Poi for Mama: a Pilot to Improve Maternal Microbiome and Gestational Diabetes Risk

Er:YAG Laser Combined With Vaginal Estriol for Genitourinary Syndrome of Menopause

Improving Menstrual and VAginal Health for All

Pesticides and Infertility: Oxidative Stress Via Circulating Cell-free DNA and Gut/Genital Microbiome Signatures in Wome…

Vulvovaginal Graft-versus-Host Disease: Diagnosis and Microbiome Evaluation

Synbiotics in Patients at RIsk fOr Preterm Birth

All recent trials (100 shown)

Vulvovaginal Candidiasis in Canadian Females

Study to Evaluate Efficacy and Safety of Gyntima® Balance in Preventing Recurrences of Bacterial Vaginosis

Vaginal Estradiol vs Moisturizer to Improve Postmenopausal Vaginal Aging Symptoms and the Microbiome in Women Living Wit…

Cytolytic Vaginosis Multicentre Registry

Microbiome Alterations With Xylitol (MAX) in Pregnancy

Vaginal Microbiome and IVF Pregnancy Outcome

Effect of Vaginal Estrogen on Alterations in the Urine Microbiome of Menopausal Women With Overactive Bladder

Genitourinary Study of Fostering Lactobacillus to Optimize the Microbiome in Women's Health (GUD-FLORA)

Efficacy and Safety of CO₂ Laser Therapy Combined With Collagen Cream in Managing Vulvo-Vaginal Atrophy: A Randomized, C…

Vaginal Care System for Menopausal Women With Urinary Tract Infections

Single Arm Trial of Menstrual Cups Among Economically Vulnerable Women to Reduce Bacterial Vaginosis and STIs

Gut Microbiome in Gynecological Cancer Patients With Pelvic Toxicity: Controls Versus Ozone Treatment. (MicrOzoGineTox)

Postbiotic Intervention on Vaginal Microbiota

FB101 Intervention in Women Screened to Have Vaginal Dysbiosis (Dyscover-3)

Vaginal Microbiome Exposure and Immune Responses in C-section Infants

Vaginal Flora for Treatment of Bacterial Vaginosis

Genital Tract Infections, the Vaginal Microbiome and Gestational Age at Birth Among Pregnant Women in South Africa

Is the Vaginal Microbiome and Metabolome Associated With Spontaneous Preterm Birth (sPTB) in Multiple Pregnancies?

Clinical Study of STI Screening to Prevent Adverse Birth and New-born Outcomes (Philani Ndiphile)

Flourish Vaginal Care System to Establish Neovaginal Microbiome