Vaginal Detection of Orally Delivered Probiotic Strains in Healthy Women

Inclusion Criteria: * Clinically healthy female between the ages of 18 and 50 years, inclusive, * have a regular or predictable menstrual cycle * Typically have regular bowel movements, * Willing and able to consume a probiotic supplement for 4 weeks, * Willing to discontinue consumption of probiotic supplement and probiotic-fortified products 2 weeks before the start of the study and throughout the study, * Willing to discontinue fiber supplements 2 weeks before the start of the study, and throughout the study, * Willing to provide 1 stool sample 4 times throughout the study, * Willing to provide 2 vaginal swabs 4 times throughout the study, * Willing to undergo vaginal pH swab measurements (with a swab) 5 times throughout the study, * Willing to provide 2 perineal skin swabs (skin between the vagina and the anus) 3 times throughout the study, * Willing to complete a pregnancy test at the screening visit. Exclusion Criteria: * Menopausal women, * Vaginal pH \< 2 or \> 5 measured at screening, •. Menstruation during the sample collection times, * Women that are lactating, pregnant, attempting to get pregnant, or have a positive pregnancy test, * Use of vaginal probiotics in the last 3 months, * Use of local vaginal antibiotics or antifungals in the last 3 months. * Use of oral antibiotics or antifungals in the last month, * Ongoing symptoms of vaginal and/or urinary tract infections, * Current treatment for vaginal sepsis or urosepsis, * Currently being treated for a se…