Neonatal Opioid Withdrawal Syndrome

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Neonatal Opioid Withdrawal Syndrome trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 2 trials

RecruitingNot Applicable

NCT07278375

Target Trial Emulation for Pharmacologic Treatment of Neonatal Opioid Withdrawal Syndrome

The goal of this observational study is to learn how two medicines used in routine care-buprenorphine and morphine-affect recovery in newborns (≥36 weeks' gesta…

United States796 participantsStarted 2025-12-09

RecruitingNot Applicable

NCT05937594

MicroRNA Biomarkers for Neonatal Opioid Withdrawal Syndrome

Infants with neonatal abstinence syndrome (NAS) experience prolonged hospital stays and poor neurodevelopmental outcomes, in-part because of the lack of accurat…

United States50 participantsStarted 2020-01-15

Treatment: Buccal swab saliva for further genetic testing

All recent trials (26 shown)

Active — Not RecruitingNot Applicable

NCT05129020

Neurostimulation to Improve NOWS Outcomes

The objective of this study is to determine if tAN therapy can reduce the median number of days of oral morphine administered to an infant after start of treatm…

United States52 participantsStarted 2022-07-27

Treatment: Sparrow Fledging Therapy System, Sham Sparrow Fledging Therapy System

Not Yet RecruitingPhase 2/3

NCT07493785

Dexmedetomidine for Invasive Ventilation In the NEOnate

Despite the increasing use of non-invasive ventilation, a large majority of premature neonates still receive invasive ventilation during their NICU (neonatal in…

France246 participantsStarted 2026-06-01

Treatment: Dexmedetomidine Injectable Solution, Glucose 5% Injectable Solution

Neonatal Opioid Withdrawal Syndrome

Trial phase breakdown

Trial status

Actively recruiting — 2 trials

Target Trial Emulation for Pharmacologic Treatment of Neonatal Opioid Withdrawal Syndrome

MicroRNA Biomarkers for Neonatal Opioid Withdrawal Syndrome

All recent trials (26 shown)

Neurostimulation to Improve NOWS Outcomes

Dexmedetomidine for Invasive Ventilation In the NEOnate

Trial phase breakdown

Trial status

Actively recruiting — 2 trials

Target Trial Emulation for Pharmacologic Treatment of Neonatal Opioid Withdrawal Syndrome

MicroRNA Biomarkers for Neonatal Opioid Withdrawal Syndrome

All recent trials (26 shown)

Neurostimulation to Improve NOWS Outcomes

Dexmedetomidine for Invasive Ventilation In the NEOnate

Medication Treatment for Opioid Use Disorder in Expectant Mothers: Conceptual Model Assessments Sub-study

Medication Treatment for Opioid Use Disorder in Expectant Mothers: Infant Neurodevelopmental Outcomes Sub-study

Testing an Arts-based Program to Reduce Nurse Stigma Towards Perinatal Substance Use

Optimizing Pharmacologic Treatment for Neonatal Opioid Withdrawal Syndrome (OPTimize NOW): A Symptom-Based Dosing Approa…

Use of SVS Device to Improve Outcomes for Neonatal Opioid Withdrawal Syndrome.

Medication Treatment for Opioid Use Disorder in Expectant Mothers

Trial to Shorten Pharmacologic Treatment of Newborns With Neonatal Opioid Withdrawal Syndrome (NOWS)

Eating, Sleeping, Consoling for Neonatal Withdrawal (ESC-NOW): a Function-Based Assessment and Management Approach

ACT NOW Longitudinal Study: Outcomes of Babies With Opioid Exposure Study

The Effect of Music Therapy on Newborns

Maternal Opioid Treatment: Human Experimental Research - Data Yield Appropriate Decisions

CHF6563 in Babies With Neonatal Opioid Withdrawal Syndrome

Randomized Control Trial of Buprenorphine vs. Morphine for the Treatment of Neonatal Opioid Withdrawal Syndrome (NOWS)

tAN to Mitigate Withdrawal Behaviors in Neonates

Optimal Morphine Dosing Schedule for Neonatal Abstinence Syndrome

Buprenorphine Pharmacometric Open Label Research Study of Drug Exposure

How to Treat Opiate Withdrawal in Neonates

Improving Outcomes in Neonatal Abstinence Syndrome