Myopia, High-Grade

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Myopia, High-Grade trials you may qualify for

100

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 17 trials

RecruitingNot Applicable

NCT06949579

Risk of Posterior Staphyloma in Highly Myopic Europeans : From Epidemiology to Anatomy.

In this cross-sectionnal study the aim is to increase the understanding of posterior staphyloma through a unique European consortium. Therefore, all eligible pa…

France200 participantsStarted 2026-02-02

Treatment: blood sampling for DNA

RecruitingNot Applicable

NCT07424755

AI-Empowered Fundus Platform

According to estimates by the World Health Organization, approximately half of the global adult population currently suffers from varying degrees of myopia. In…

China1,000 participantsStarted 2024-10-01

Treatment: Multimodal Ocular Imaging and Biometry with Aritifical Intelligence Analysis

RecruitingPhase 1/2

NCT06523504

Atropine (0.02%, 0.04%) Combined With Defocus DIMS for Moderate and High Myopia Control

To evaluate the effectiveness and safety of DIMS, low concentration atropine eye drops,and atropine combined with DIMS in controlling axial length and refractio…

China410 participantsStarted 2024-02-01

Treatment: DIMS, The 0.02% ATP Group

RecruitingNot Applicable

NCT07052825

The Role of Capsular Tension Rings in Intraocular Lens Stability in High Myopia Cataract Patients: A Prospective Self-Co…

Study Purpose: This prospective, self-controlled clinical study aims to evaluate the impact of capsular tension rings (CTR) on intraocular lens (IOL) stability…

China120 participantsStarted 2025-01-01

Treatment: CTR implantation

RecruitingNot Applicable

NCT06264830

3D Visualization System in Highly Myopic Cataract Operation

This study aims to investigate the impact of depth of field differences between the use of the 3D imaging system (NGENUITY® 3D Visualization System, Alcon, TX,…

Taiwan45 participantsStarted 2024-07-03

Treatment: Alcon-NGENUITY®(NG)-system, Standard cataract operation

RecruitingNot Applicable

NCT06322433

Follow up of High Myopic Eyes

In this non-interventional retrospective and prospective observational study, the long-term evolution of clinical and iconographic characteristics of patients w…

Italy138 participantsStarted 2023-11-01

Treatment: no drugs used for this study

All recent trials (100 shown)

Active — Not RecruitingNot Applicable

NCT07129798

Efficacy and Safety of Myopic Macular Hole Closure Surgery Without Endotamponade Agent

Macular hole (MH) is a common condition that affects approximately 1.6/1000 elderly Chinese population. The prevalence is expected to be even higher in individu…

Hong Kong20 participantsStarted 2024-01-18

Treatment: ILM flap with no endotamponade technique

Active — Not RecruitingNot Applicable

NCT05850936

Effect of IOP Lowering on Progressive HM

Currently, whether and when intraocular pressure (IOP) lowering medication should be used in progressive high myopia (HM) to control axial elongation is still a…

China152 participantsStarted 2023-06-01

Treatment: Assigned Interventions: IOP-lowering eye drops

Myopia, High-Grade

Trial phase breakdown

Trial status

Actively recruiting — 17 trials

Risk of Posterior Staphyloma in Highly Myopic Europeans : From Epidemiology to Anatomy.

AI-Empowered Fundus Platform

Atropine (0.02%, 0.04%) Combined With Defocus DIMS for Moderate and High Myopia Control

The Role of Capsular Tension Rings in Intraocular Lens Stability in High Myopia Cataract Patients: A Prospective Self-Co…

3D Visualization System in Highly Myopic Cataract Operation

Follow up of High Myopic Eyes

All recent trials (100 shown)

Efficacy and Safety of Myopic Macular Hole Closure Surgery Without Endotamponade Agent

Effect of IOP Lowering on Progressive HM

Trial phase breakdown

Trial status

Actively recruiting — 17 trials

Risk of Posterior Staphyloma in Highly Myopic Europeans : From Epidemiology to Anatomy.

AI-Empowered Fundus Platform

Atropine (0.02%, 0.04%) Combined With Defocus DIMS for Moderate and High Myopia Control

The Role of Capsular Tension Rings in Intraocular Lens Stability in High Myopia Cataract Patients: A Prospective Self-Co…

3D Visualization System in Highly Myopic Cataract Operation

Follow up of High Myopic Eyes

All recent trials (100 shown)

Efficacy and Safety of Myopic Macular Hole Closure Surgery Without Endotamponade Agent

Effect of IOP Lowering on Progressive HM

The Effect and Safety of Different Doses of Atropine on Myopic Progression of Highly Myopic Children: Multi-centered Ran…

Low Concentration Atropine Combined With Soft Contact Lens in Controlling Myopia Progression in Children With High Myopi…

Photorefractive Keratectomy for Severe Anisometropia and Isoametropia Associated With Amblyopia

Visual Outcomes of an Enhanced Monofocal Intraocular Lens Targeted for Monovision in Highly Myopic Eyes: a Randomized Co…

Evaluation of Toric Intraocular Lens(IOL) Combined With Capsular Tension Ring(CTR) in Patients With Cataract Combined Wi…

Efficacy and Safety of Spectacle Lenses With H.A.L.T. MAX Technology on High Myopia Control in Children and Adolescents

Comparison of Retinal Damage in ICL Implantation Using 3D Visualization System vs. Microscope

100 High Myopia Patient-reported Outcomes (PRO) and Performance Outcomes (PERFO)

AOSLO-Based Precise Measurement of Retinal Hemodynamics: Development and Application Assessment

Evaluation of Eye Health Benefits of Black Tomato Extract

Comparing Monofocal IOLs in Highly Myopic Cataract Patients

Repeated Low-Level Red-Light Therapy for Shortening Axial Length

The Influence of Axial Length on Visual Quality Following SMILE Surgery in Patients with High Myopia

Visual Quality of Cataract Patients with High Myopia After Implantation of Different Intraocular Lenses

Anterior Segment and Corneal Parameters in Keratoconus and High Myopic Astigmatism Using Schiempflug Imaging

Effect of Low-level Red-light on Ultra-high Myopia

Myopic Optic Neuropathy in Chinese High Myopia Population

Efficacy and Safety of Intravitreal Bevacizumab in the Treatment of Choroidal Neovascular Membranes Associated to High M…