100 High Myopia Patient-reported Outcomes (PRO) and Performance Outcomes (PERFO) (NCT07101146) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
100 High Myopia Patient-reported Outcomes (PRO) and Performance Outcomes (PERFO)
100 participantsStarted 2025-10
Plain-language summary
Prospective, longitudinal, interventional, exploratory, non-randomized, single-center study including patients with pathological myopia .
Who can participate
Age range18 Years – 55 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
Patients with pathological myopia and diffuse choroidal atrophy (DCA, Cat. 2 Meta PM)
* Age ≥ 18 years and ≤ 55 years;
* Patient consenting to be included in the study;
* Examination and follow-up in at least one of the participating centers;
* Severe pathological myopia with an axial length ≥ 26.5 mm in both eyes;
* Presence of diffuse atrophy (category 2 of the Meta-PM classification) in the better eye;
* Affiliated with or covered by a social security system.
Pathological myopic patients with patch choroidal atrophy (PCA,
Cat. 3 Meta PM):
* Age ≥ 18 years and ≤ 55 years;
* Patients who consent to be included in the study;
* Examination and follow-up at least one of the participating centers;
* High myopia with an axial length ≥ 26.5 mm in both eyes;
* Presence of patch atrophy (category 3 of the Meta-PM classification) in the better eye;
* Affiliated with or beneficiary of a social security system.
Exclusion Criteria:
* Identified genetic syndromic myopia, including Stickler syndromes type 1 and 2 (collagen 2A1 and 11A1), Marfan syndrome (fibrillin), Ehler-Danlos syndrome type 4 (lysyl-protocollagen hydroxylase), and Knobloch syndrome (collagen 18A).
* Patient unwilling to participate or be followed up at one of the participating centers.
* Binocular visual acuity ≥ 1 logMar (\<0.1 on the decimal scale).
* Media opacities preventing quality imaging, including cataracts.
* Patients benefiting from legal protection measures.
* Pregnant or breastfee…
What they're measuring
1
Simulator driving test:Evaluation of pedestrian detection performance using peripheral vision
Timeframe: 2 months
2
Locomotion assessment
Timeframe: 2 months
3
Visual search in VR
Timeframe: 2 months
Trial details
NCT IDNCT07101146
SponsorCentre Hospitalier National d'Ophtalmologie des Quinze-Vingts