Active — Not RecruitingNot Applicable

Repeated Low-Level Red-Light Therapy for Shortening Axial Length

China30 participantsStarted 2022-11-19

Plain-language summary

The purpose of this clinical trial is to confirm the incidence and magnitude of axial length shortening after RLRL therapy in Chinese high myopia children and teenagers.

Who can participate

Age range6 Years – 16 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Provision of consent.
✓. Age: ≥ 6 and ≤ 16 years at enrolment.
✓. High myopia: cycloplegic sphere ≤ -6.00 diopters (D) in both eyes.
✓. Willing and able to participate in all required activities of the study.
✓. The children currently on myopia control treatment can be recruited if myopia control treatments (including but not limited to atropine, orthokeratology, rigid gas-permeable lenses, defocus spectacles, etc.) are discontinued for at least 2 weeks.
✓. Normal fundus, tessellated fundus or with peripapillary diffuse chorioretinal atrophy.

Exclusion criteria

✕. Secondary myopia, such as a history of retinopathy of prematurity or neonatal problems, or syndromic myopia with a known genetic disease or connective tissue disorders, such as Stickler or Marfan syndrome.
✕. Pathologic myopia with signs of macula-involving diffuse chorioretinal atrophy, patchy chorioretinal atrophy, macular atrophy, lacquer cracks, myopic choroidal neovascularization or Fuchs' spots.
✕. Strabismus and binocular vision abnormalities in either eye.
✕. Previous any intraocular surgery affecting refractive status.
✕. Other reasons, including but not limited to ocular or other systemic abnormalities, that the physician may consider inappropriate for enrolment.

What they're measuring

Incidence rate (%) of axial length shortening >0.05 mm measured by the IOL Master

Timeframe: 12 months

Trial details

NCT IDNCT05550740

SponsorShanghai Eye Disease Prevention and Treatment Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-03-01

View on ClinicalTrials.gov More High Myopia trials