Early-Onset Neonatal Sepsis

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Early-Onset Neonatal Sepsis trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 4 trials

RecruitingNot Applicable

NCT06100614

Presepsin to Safely Reduce Antibiotics in Preterm Infants

In the Netherlands, more than 85% of the preterm infants born \<32 weeks gestational age get antibiotics directly after birth because of the risk of infection w…

Netherlands900 participantsStarted 2024-09-23

Treatment: Presepsin, Standard Care

RecruitingNot Applicable

NCT06845332

Promoting Optimal Treatment Choices in Neonates With Suspected Early-Onset Sepsis

In this study, three neonatal evidence-based antibiotic stewardship strategies will be implemented in Dutch hospitals. These include the early-onset sepsis (EOS…

Netherlands55,000 participantsStarted 2024-01-01

RecruitingNot Applicable

NCT07152106

Amniotic Fluid & the Preterm Gut

Background: Necrotizing enterocolitis (NEC) and sepsis in preterm infants have been linked to intestinal immaturity and preclinical gut microbiota alterations.…

Netherlands275 participantsStarted 2024-10-14

RecruitingNot Applicable

NCT06076200

Population Pharmacokinetic of Piperacillin/Tazobactam in Maternal and Neonatal Populations

The purpose of this study is to describe the population pharmacokinetic characteristics of piperacillin/tazobactam after intravenous administration in pregnant…

China50 participantsStarted 2023-09-30

Treatment: Piperacillin Sodium and Tazobactam Sodium for Injection

All recent trials (45 shown)

CompletedPhase 4

NCT03997266

NICU Antibiotics and Outcomes Trial

The goal of the NANO trial is to study the longstanding clinical practice of empirically administering intravenous antibiotics to extremely low birthweight (ELB…

United States359 participantsStarted 2020-08-05

Treatment: Ampicillin, Gentamycin

Not Yet RecruitingNot Applicable

NCT06643052

Cahnge in Management of Suspected Early Onset Neonetal Sepsis After Assimilation of Early Onset Sepsis Calculator

Early neonatal sepsis requires rapid and efficient intervention to prevent morbidity and mortality. Management of such a case includes invasive blood examinatio…

Israel6,300 participantsStarted 2026-12-01

Treatment: No intervention

Early-Onset Neonatal Sepsis

Trial phase breakdown

Trial status

Actively recruiting — 4 trials

Presepsin to Safely Reduce Antibiotics in Preterm Infants

Promoting Optimal Treatment Choices in Neonates With Suspected Early-Onset Sepsis

Amniotic Fluid & the Preterm Gut

Population Pharmacokinetic of Piperacillin/Tazobactam in Maternal and Neonatal Populations

All recent trials (45 shown)

NICU Antibiotics and Outcomes Trial

Cahnge in Management of Suspected Early Onset Neonetal Sepsis After Assimilation of Early Onset Sepsis Calculator

Trial phase breakdown

Trial status

Actively recruiting — 4 trials

Presepsin to Safely Reduce Antibiotics in Preterm Infants

Promoting Optimal Treatment Choices in Neonates With Suspected Early-Onset Sepsis

Amniotic Fluid & the Preterm Gut

Population Pharmacokinetic of Piperacillin/Tazobactam in Maternal and Neonatal Populations

All recent trials (45 shown)

NICU Antibiotics and Outcomes Trial

Cahnge in Management of Suspected Early Onset Neonetal Sepsis After Assimilation of Early Onset Sepsis Calculator

Extended Interval Dosing of Gentamicin in Neonates

Individualized Duration of Antibiotic Treatment in Early Onset Infection in Newborns.

Early Hydrocortisone Versus Regular Treatment in Shock in Extremely Preterm Neonates - an Open Randomized Controlled Tri…

The Peripheral(-Muscle) Oxygenation and Perfusion Score as a New Non-invasive Tool to Predict Elevations in C-reactive P…

Serosurveillance Study of Maternally Derived Anti-GBS Antibody

Efficacy And Safety Of Short Course Antibiotic Therapy In Preterm Neonates With Early Onset Sepsis

Using Machine Learning to Model Early-onset Neonatal Sepsis Risk in Uganda and Zimbabwe

Neonatal Sepsis and GBS Carriage Study

Selective Antibiotics When Symptoms Develop Versus Universal Antibiotics for Preterm Neonates

Safely Reduce Newborn Antibiotic Exposure With the Early-onset Sepsis Calculator

Maternal, Neonatal and Infant Outcomes at Kawempe National Referral Hospital

Serocorrelate of Protection Against GBS (PREPARE WP3)

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care

Molecular Culture for the Diagnosis of Neonatal Sepsis

Predicting EONS in PPROM Patients

PROcalcitonin and Presepsin-guided Decision for Antibiotic Prophylaxis of EOS

A Chart Review of Newborns With the Presence of Confirmed or Suspected Maternal Chorioamnionitis and Utilization of the…

Performance of Interleukin-27 Cord Blood Level as A Biomarker Predicating Early Onset Neonatal Sepsis