Cigarette Smoker

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Cigarette Smoker trials you may qualify for

100

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 28 trials

RecruitingNot Applicable

NCT04163081

The INITIATE Study: Initiating Nicotine Dependence Treatment for Smokers Admitted to Emergency Departments

The INITIATE Study is a randomized controlled trial that is testing an intervention designed to increase long-term abstinence among tobacco smokers seen in emer…

Canada1,208 participantsStarted 2022-04-19

Treatment: Quit Card Intervention (QCI)

RecruitingNot Applicable

NCT07443631

Assessment of HPHC Exposure in Smokers Switching to THS/TP18 With Different Device Variants

This is a randomized, controlled, open-label, 6 parallel arms study to assess reduced exposure of biomarkers of exposure (BoE) of selected HPHC in smokers switc…

United Kingdom108 participantsStarted 2026-02-19

Treatment: THS1 (TP18 variant 1), THS2 (TP18 variant 2)

RecruitingNot Applicable

NCT07562295

Periodontal Health Among Cigarette, Electronic Cigarettes, and Narghile Smokers

This study compares the different effects of traditional cigarettes, e-cigarettes, and narghile on periodontal health among a sample of Al-Hawash Private Univer…

Syria90 participantsStarted 2025-06-01

Treatment: Non-Interventional Study

RecruitingPhase 2

NCT06296849

Dyadic Financial Incentive Treatments for Dual Smoker Couples

Smokers partnered with other smokers (i.e., dual-smoker couples) represent \~2/3 of all smokers. Dual-smoker couples (DSCs) are less likely to try to quit smoki…

United States900 participantsStarted 2024-01-18

Treatment: Financial Incentive Treatment (FIT)

RecruitingNot Applicable

NCT07547202

Effect of Non-Surgical Periodontal Therapy on Salivary Biomarkers in Smokers and Non-Smokers With Periodontitis

This study evaluates the effect of non-surgical periodontal therapy on salivary biomarkers (Dkk-1, Sclerostin, and PLAP-1) and clinical periodontal parameters i…

Iraq44 participantsStarted 2026-01-01

Treatment: Non-surgical periodontal therapy (Scaling and root planing)

RecruitingNot Applicable

NCT05660525

Leveraging Community Pharmacists to Optimize Smoking Cessation Services for Rural Smokers in Appalachia

The goal of this clinical trial is to evaluate the effectiveness and implementation of a pharmacist-delivered MTM (medication therapy management) approach, call…

United States768 participantsStarted 2024-03-06

Treatment: 4 weeks of Nicotine lozenge, 8 weeks of Nicotine Replacement Therapy Patch

All recent trials (100 shown)

Not Yet RecruitingNot Applicable

NCT07553819

Home-Based Respiratory Muscle Training and Aerobic Exercise Programs to Improve Lung Health in Current and Former Cigare…

This clinical trial studies whether home-based respiratory muscle training (RMT) and aerobic exercise (AE) programs can be used to improve lung health in curren…

United States200 participantsStarted 2026-05-01

Treatment: Accelerometry, Aerobic Exercise

CompletedPhase 4

NCT02271919

Varenicline and Combined NRT for Smoking Cessation

This randomized pilot phase IV trial studies the side effects and how well varenicline works compared to nicotine replacement therapy in helping patients that s…

United States631 participantsStarted 2015-05-14

Treatment: Nicotine Lozenge, Nicotine Patch

Cigarette Smoker

Trial phase breakdown

Trial status

Actively recruiting — 28 trials

The INITIATE Study: Initiating Nicotine Dependence Treatment for Smokers Admitted to Emergency Departments

Assessment of HPHC Exposure in Smokers Switching to THS/TP18 With Different Device Variants

Periodontal Health Among Cigarette, Electronic Cigarettes, and Narghile Smokers

Dyadic Financial Incentive Treatments for Dual Smoker Couples

Effect of Non-Surgical Periodontal Therapy on Salivary Biomarkers in Smokers and Non-Smokers With Periodontitis

Leveraging Community Pharmacists to Optimize Smoking Cessation Services for Rural Smokers in Appalachia

All recent trials (100 shown)

Home-Based Respiratory Muscle Training and Aerobic Exercise Programs to Improve Lung Health in Current and Former Cigare…

Varenicline and Combined NRT for Smoking Cessation

Trial phase breakdown

Trial status

Actively recruiting — 28 trials

The INITIATE Study: Initiating Nicotine Dependence Treatment for Smokers Admitted to Emergency Departments

Assessment of HPHC Exposure in Smokers Switching to THS/TP18 With Different Device Variants

Periodontal Health Among Cigarette, Electronic Cigarettes, and Narghile Smokers

Dyadic Financial Incentive Treatments for Dual Smoker Couples

Effect of Non-Surgical Periodontal Therapy on Salivary Biomarkers in Smokers and Non-Smokers With Periodontitis

Leveraging Community Pharmacists to Optimize Smoking Cessation Services for Rural Smokers in Appalachia

All recent trials (100 shown)

Home-Based Respiratory Muscle Training and Aerobic Exercise Programs to Improve Lung Health in Current and Former Cigare…

Varenicline and Combined NRT for Smoking Cessation

Bronchoscopy in Determining the Effect of E-Cigarette Smoking on Biomarkers in the Lungs

Potential Effects of Electronic Nicotine Delivery System Flavor Regulations on African American Menthol Smokers

Risk and Benefits of Electronic Cigarettes to Older Smokers at High Risk for Lung Cancer

Effects of Electronic Cigarette Flavors on Abuse Liability in Smokers (P3-Taste)

Nicotine and Tobacco Message Framing to Change Smoking Behavior in Diverse Groups of Young Adult Smokers

Pharmacokinetic and Subjective Effects of Heated Tobacco Products

A Behavioral Application for Improving Smoking Cessation Among Smokers

Mapping Brain Glutamate in Humans: Sex Differences in Cigarette Smokers

Understanding How Cigarette Direct Mail Marketing Influences Smoking Behaviors Among High and Low Socioeconomic Status Y…

Potential Impact of Menthol Ban in Cigarettes and E-cigarettes

A Novel Tobacco Cessation Resource for Smokers With a Diagnosed or Suspected Thoracic Cancer

A RCT to Determine the Effect of ENDS Flavor Availability on Abstinence Within Smokers

SMOKING AND PRESENCE OF FRANK'S SIGN

Evaluation of Canakinumab in High-Risk Former-Smokers

Predictors and Consequences of Combustible Cigarette Smokers' Switch to Standardized Research E-Cigarettes

Tabata Exercise on Nitric Oxide Synthases and Maresin

rTMS in Promoting Smoking Cessation and Preventing Relapse in Current Smokers

Evaluating the Episodic Future Thinking Intervention for Reducing Cigarette Consumption in Cigarette Smokers