A Behavioral Application for Improving Smoking Cessation Among Smokers (NCT07493252) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
A Behavioral Application for Improving Smoking Cessation Among Smokers
United States1,812 participantsStarted 2026-08-01
Plain-language summary
This clinical trial compares two smartphone applications, called Actify! (A \& B) for improving smoking cessation outcomes in individuals who smoke. Actify! A is an app grounded in behavioral activation therapy, an evidence-based treatment for depression that can also be used to modify health behaviors such as smoking. The Actify! B app provides evidence-based tobacco cessation strategies based on current clinical guidelines.
Who can participate
Age range18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age 18 or older
* Currently smoke, averaging at least 5 cigarettes/day for the last 30 days
* Interested in quitting smoking in the next 30 days
* Experience downloading and using one or more apps on their smartphone
* Either screens negative for depression (Patient Health Questionnaire - 9 item \[PHQ-9\] score 0-4; n = 906) or screens positive for mild to moderately severe current depressive symptoms (PHQ-9 score 5-19; n = 906)
* Willing and able to complete all study activities and to receive compensation by mail
* Comfortable reading and writing in English
* Have a mobile data plan and/or access to WiFi to support the use of the assigned app
* Reside in the United States (US)
* Willing to provide information for an emergency contact in case of serious concerns about the participant's physical or mental health
Exclusion Criteria:
* Self-report of currently receiving behavioral treatment for depression (e.g., psychotherapy or counseling, web- or app-based interventions); current use of pharmacotherapy for depression or for other mental health conditions that are not otherwise excluded is allowable (e.g., benzodiazepines, anticonvulsants, opioid agonists, antipsychotics)
* Severe depression (PHQ-9 ≥ 20)
* Current suicidal ideation reported on the PHQ-9
* History of a suicide attempt
* Self-reported lifetime diagnosis of bipolar disorder, schizophrenia, schizoaffective disorder, antisocial personality disorder, or borderline personality disorder; or se…
What they're measuring
1
Self-reported 30-day point prevalence abstinence (PPA) from cigarette smoking