ADME

Clinical trial pipeline · Data from ClinicalTrials.gov

See which ADME trials you may qualify for

100

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 3 trials

RecruitingPhase 1

NCT06672523

A Study to Evaluate the Mass Balance, Metabolism, Elimination, and Drug Levels of [14C]-BMS-986504 (MRTX1719) in Partici…

The purpose of this study is to evaluate the mass balance, metabolism, elimination, and drug levels of \[14C\]-BMS-986504 (MRTX1719) in participants with advanc…

Hungary, Spain8 participantsStarted 2025-03-24

Treatment: BMS-986504, [14C]-BMS-986504

RecruitingPhase 1

NCT06713369

AZD5305 hADME in Patients With Advanced Solid Malignancies

This Phase I, open-label study aims to study to absolute bioavailability of Saruparib (AZD5305) and the absorption, distribution, metabolism and excretion (ADME…

United Kingdom8 participantsStarted 2025-04-02

Treatment: Saruparib (AZD5305), [14C]-AZD5305 microtracer

RecruitingNot Applicable

NCT04154553

Pharmacogenetic Testing of Patients With Unwanted Adverse Drug Reactions or Therapy Failure

Genetic makeup of a patient influences the efficacy and safety profile of a drug. This study is to summarize individual cases, where Pharmacogenetics (PGx) has…

Switzerland400 participantsStarted 2019-10-15

Treatment: Buccal swab, EDTA Blood sample (4.9mL)

All recent trials (100 shown)

CompletedPhase 1

NCT06308263

Tuvusertib (M1774) Human Mass Balance and Absolute Bioavailability Study (DDRIVER Solid Tumors 303)

This is a single sequence 2-period open label study in participants with advanced solid tumors. The purpose of Period 1 of this study is to assess the mass bala…

Hungary12 participantsStarted 2024-03-25

Treatment: Tuvusertib [14C]Tuvusertib microtracer, Tuvusertib

CompletedPhase 1

NCT07130097

A Study to Compare Two Tablet Formulations of Study Medicine Atirmociclib in Healthy Participants

The purpose of this study is to understand bioequivalence (medicines that may have different names or be made in different ways, but have the same effect on the…

United States35 participantsStarted 2025-08-14

Treatment: PF-07220060

ADME

Trial phase breakdown

Trial status

Actively recruiting — 3 trials

A Study to Evaluate the Mass Balance, Metabolism, Elimination, and Drug Levels of [14C]-BMS-986504 (MRTX1719) in Partici…

AZD5305 hADME in Patients With Advanced Solid Malignancies

Pharmacogenetic Testing of Patients With Unwanted Adverse Drug Reactions or Therapy Failure

All recent trials (100 shown)

Tuvusertib (M1774) Human Mass Balance and Absolute Bioavailability Study (DDRIVER Solid Tumors 303)

A Study to Compare Two Tablet Formulations of Study Medicine Atirmociclib in Healthy Participants

Trial phase breakdown

Trial status

Actively recruiting — 3 trials

A Study to Evaluate the Mass Balance, Metabolism, Elimination, and Drug Levels of [14C]-BMS-986504 (MRTX1719) in Partici…

AZD5305 hADME in Patients With Advanced Solid Malignancies

Pharmacogenetic Testing of Patients With Unwanted Adverse Drug Reactions or Therapy Failure

All recent trials (100 shown)

Tuvusertib (M1774) Human Mass Balance and Absolute Bioavailability Study (DDRIVER Solid Tumors 303)

A Study to Compare Two Tablet Formulations of Study Medicine Atirmociclib in Healthy Participants

A Study of Absorption, Distribution, Metabolism and Excretion (ADME) of [14C]AZD4144

A Study to Understand What the Body Does to the Study Medicine Called PF-07220060 When Taken by Healthy Adults

A Study to Understand How the Body Processes [14C]PF-07104091 in Healthy Participants

An Absorption, Distribution, Metabolism, Excretion (ADME) Study of [14C]Subasumstat in Adults With Advanced or Metastati…

A Study of Absorption-Distribution-Metabolism-Excretion (ADME) of [14C]IMP4297 to China Healthy Male Subjects

Mass Balance Study of [14C]Xeruborbactam (QPX7728) in Healthy Adult Male Participants

An ADME Study of [14C]AZD0780 in Healthy Male Subjects

A Study to Evaluate Metabolism, Excretion, and Mass Balance of [14C]Vapendavir

A Study to Assess the Mass Balance and ADME of [14C]AZD5004 and the Absolute Bioavailability of AZD5004

A Study to Evaluate the Drug Levels, Metabolism and Excretion, and Absolute Bioavailability of BMS-986365 in Healthy Mal…

Single Dose Study of [14C]-IDV184001AN ([14C]-IDV184001) in Healthy Adult Male Participants

A Study to Learn How the Medicine Called [14C] PF-06821497 is Taken up Into and Removed From the Body.

A Study in People With Advanced Cancer to Test How BI 907828 is Processed in the Body

A Study of [14C]-LY3866288 in Healthy Participants

A GBT021601 ADME Microtracer Study in Healthy Volunteers

Human ADME Study of [14C]-Ceralasertib (AZD6738) and Absolute Bioavailability of Ceralasertib

Single Dose ADME Study of [14C]-Rencofilstat in Healthy Male Subjects

A Study in Healthy Adult Male Participants to Assess Absorption, Distribution, Metabolism and Excretion (ADME) of Radiol…