Schizophrenia Prodromal

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Schizophrenia Prodromal trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 7 trials

RecruitingNot Applicable

NCT01730781

Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning

The aim of the present study is to assess the availability of cannabinoid receptors (CB1R) in the human brain. CB1R are present in everyone's brain, regardless…

United States100 participantsStarted 2010-07

Treatment: [11-C]OMAR

RecruitingNot Applicable

NCT05142735

Effects of NAC on Symptoms of CHR Patients

Schizophrenia is a chronic debilitating psychotic disorder. Identifying persons with "clinical high-risk" (CHR) symptoms, which are like those of schizophrenia…

Canada90 participantsStarted 2023-01-13

Treatment: N-Acetylcysteine, Placebo

RecruitingPhase 2

NCT05052853

Early Intervention of Prodromal Schizophrenia Using an NMDA Enhancer

Previous studies found that some NMDA-enhancing agents were able to improve clinical symptoms of patients with schizophrenia. Whether treatment of an NMDA-enhan…

Taiwan48 participantsStarted 2021-11-01

Treatment: NMDAE, Placebo Cap

RecruitingNot Applicable

NCT05131035

Targeting Processing Speed Deficits to Improve Social Functioning and Lower Psychosis Risk

This 10 week intervention, Specific Cognitive Remediation with Surround (or SCORES), is designed to target processing speed, a cognitive domain related directly…

United States54 participantsStarted 2021-10-28

Treatment: SCORES (Specific COgnitive Remediation with Support)

RecruitingNot Applicable

NCT05340348

Patientheque in Patients With a Psychosis .

Establishment of a patient library for patients who have had a first psychotic episode and who have an "at risk" status for psychotic disorder (GRD, APS, BLIPS…

France250 participantsStarted 2022-07-25

Treatment: Blood samples (36 mL) + fecal samples + hair sample

RecruitingNot Applicable

NCT03525054

Semantic and Syntactic Computerized Analysis of Free Speech

Subtle speech disorganization could be predictive of a transition to schizophrenia of ultra-high-risk patients. The aim of our longitudinal multicenter cohort s…

France150 participantsStarted 2018-05-18

All recent trials (41 shown)

SuspendedPhase 1/2

NCT05567848

Accelerated TMS in Psychosis

This study is to determine the tolerability and efficacy of an accelerated schedule of Transcranial Magnetic Stimulation for treating symptoms of psychotic diso…

United States20 participantsStarted 2022-11-29

Treatment: repetitive Transcranial Magnetic Stimulation (rTMS)

Not Yet RecruitingNot Applicable

NCT07157293

Online Intervention To Improve Motivation

Participants will complete one online intervention lasting 12 weeks. Each week, they will be asked to complete a 20-30 minute session online. The intervention i…

United States60 participantsStarted 2026-06

Treatment: Online Motivation Enhancing Intervention

Schizophrenia Prodromal

Trial phase breakdown

Trial status

Actively recruiting — 7 trials

Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning

Effects of NAC on Symptoms of CHR Patients

Early Intervention of Prodromal Schizophrenia Using an NMDA Enhancer

Targeting Processing Speed Deficits to Improve Social Functioning and Lower Psychosis Risk

Patientheque in Patients With a Psychosis .

Semantic and Syntactic Computerized Analysis of Free Speech

All recent trials (41 shown)

Accelerated TMS in Psychosis

Online Intervention To Improve Motivation

Trial phase breakdown

Trial status

Actively recruiting — 7 trials

Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning

Effects of NAC on Symptoms of CHR Patients

Early Intervention of Prodromal Schizophrenia Using an NMDA Enhancer

Targeting Processing Speed Deficits to Improve Social Functioning and Lower Psychosis Risk

Patientheque in Patients With a Psychosis .

Semantic and Syntactic Computerized Analysis of Free Speech

All recent trials (41 shown)

Accelerated TMS in Psychosis

Online Intervention To Improve Motivation

Perception and Integration of Sensory Information in the Early Stages of Psychosis

Evaluation of Step-Based Care for Individuals at Clinical High Risk for Psychosis

Family-Focused Therapy for Individuals at High Clinical Risk for Psychosis: A Confirmatory Efficacy Trial

DMHI for At-Risk College Students

EPI-MINN: Targeting Cognition and Motivation - National

Face Your Fears: Cognitive Behavioural Virtual Reality Therapy for "Paranoia".

REtinal and VIsual Cortical Response in Early PSYchosis

Feasibility Trial of a Lifestyle Intervention for CHR-P

Neurofeedback Training for High Risk Psychosis

Investigating the Role of Diazepam on Brain Function and Chemistry in Psychosis Risk

Repetitive Transcranial Magnetic Stimulation in Early Psychosis and The Functional Connectivity Biotypes

Ziprasidone in the Psychosis Prodrome

"Multimodal Prevention of Psychosis - Investigating Efficacy of N-Acetylcysteine and Psychotherapy in CHR-Patients"

Early Detection and Intervention for Women At-risk of Psychosis

NAPLS Omega-3 Fatty Acid Versus Placebo Study

Multi-site Communication Deficits in Schizophrenia

Compensatory Cognitive Training in Clinical High Risk Latino Youth

HOPE TEAM - Clinical High Risk Group CBSST