RecruitingNot Applicable

Targeting Processing Speed Deficits to Improve Social Functioning and Lower Psychosis Risk

United States54 participantsStarted 2021-10-28

Plain-language summary

This 10 week intervention, Specific Cognitive Remediation with Surround (or SCORES), is designed to target processing speed, a cognitive domain related directly to social functioning, which in turn, represents a vulnerability factor for psychosis. This remotely-delivered intervention combining targeted cognitive training exercises and group support was developed to directly impact processing speed, and at the same time, boost motivation and engagement in adolescents at risk for schizophrenia and other psychotic disorders.

Who can participate

Age range14 Years – 20 Years

SexALL

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Inclusion Criteria: * Meet Clinical High Risk (CHR) criteria on the Structured Interview for Psychosis Risk Syndromes, defined by the presence of at least one attenuated positive symptom at a moderate to severe level * A score representing 0.5 SD below the mean on Animal Naming, Trails A or BACS: Symbol Coding from the MATRICS Consensus Cognitive Battery (MCCB). Exclusion Criteria: * Any DSM 5 Schizophrenia-Spectrum diagnosis * Non-English speaking * Past or current history of a clinically significant central nervous system disorder (e.g., seizure disorder) * Estimated IQ\<70 * Significant head injury * Significant substance abuse * Significant visual or auditory impairment.

What they're measuring

Processing Speed domain score from the MATRICS Consensus Cognitive Battery (MCCB)

Timeframe: Baseline, Mid-Treatment (5 weeks), Post Treatment (10 weeks)

Trial details

NCT IDNCT05131035

SponsorNorthwell Health

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-05-31

Contact for this trial

Ricardo E Carrion, Ph.D.

718-470-8788 rcarrion@northwell.edu