PrEP Adherence

Clinical trial pipeline · Data from ClinicalTrials.gov

See which PrEP Adherence trials you may qualify for

100

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 16 trials

RecruitingNot Applicable

NCT07509827

Evaluation of mHealth Intervention to Promote HIV Prevention and Overcome Stigma Among Transgender Women (EMPOW.HER)

This study aims to develop and evaluate a multi-component mHealth intervention (mHC and FRESH) to reduce HIV-related and intersectional stigma and improve PrEP…

Thailand108 participantsStarted 2024-08-01

Treatment: Mobile Healthy Choices (mHC)+SPC, FRESH + SPC

RecruitingNot Applicable

NCT06226155

Adaptation of an Intervention Addressing Barriers to PrEP Use Among Pregnant Women in Zimbabwe

The purpose of this study is to develop a multi-level PrEP adherence and persistence intervention as an adaptation of the TENDAI ('grateful' in Shona) program,…

Zimbabwe132 participantsStarted 2024-10-21

Treatment: TENDAI4PrEP, Enhanced treatment as usual

RecruitingNot Applicable

NCT07002866

Suubi4PrEP: Improving PrEP Access and Adherence Among Adolescent Girls and Young Women in Uganda

The study will employ a multilevel combination intervention focused on PrEP initiation and adherence among adolescent girls and young women (AGYW) (aged 15-24)…

United States, Uganda600 participantsStarted 2025-10-20

Treatment: HIV Risk Reduction (HIVRR), PrEP Peer Supporters (PS)

RecruitingNot Applicable

NCT07186244

Prevention ICONA Dedicated Ensemble

Despite significant advances in HIV treatment, transmission remains a public health concern. In 2022, there were 1.3 million new HIV infections worldwide and 1,…

Italy5,000 participantsStarted 2024-09-09

RecruitingNot Applicable

NCT05165745

Stick2PrEP Cisgender Women and Trans Individuals

Taking a daily anti-HIV pill can protect people from HIV infection. This is called preexposure prophylaxis \[PrEP\]. Many cisgender women and trans individuals…

United States175 participantsStarted 2021-10-25

Treatment: Individualized Feedback

RecruitingPhase 3

NCT06919614

STI Testing to Enhance PrEP Use in Pregnancy

The investigators are conducting a study in Botswana to see if offering STI testing along with expanded HIV prevention options (PrEP) helps more pregnant women…

Botswana600 participantsStarted 2025-06-18

Treatment: Chlamydia trachomatis, Neisseria gonorrhoeae and Trichomonas vaginalis testing

All recent trials (100 shown)

CompletedNot Applicable

NCT04899024

PrEP Affect Regulation Treatment Innovation

This multi-site randomized controlled trial enrolling sexual minority men who use stimulants and are currently taking pre-exposure prophylaxis (PrEP). This rand…

United States239 participantsStarted 2022-01-31

Treatment: PARTI, Attention-Control

Active — Not RecruitingNot Applicable

NCT04738825

Promoting HIV Risk Reduction Among People Who Inject Drugs: A Stepped Care Approach Using Contingency Management With Pr…

The proposed study will be a 24-week intervention with a 12-month follow-up period to evaluate the impact of contingency management with stepped care to pre-exp…

United States526 participantsStarted 2021-10-04

Treatment: Contingency Management with stepped care to PrEP adherence and support services (CoMPASS)

PrEP Adherence

Trial phase breakdown

Trial status

Actively recruiting — 16 trials

Evaluation of mHealth Intervention to Promote HIV Prevention and Overcome Stigma Among Transgender Women (EMPOW.HER)

Adaptation of an Intervention Addressing Barriers to PrEP Use Among Pregnant Women in Zimbabwe

Suubi4PrEP: Improving PrEP Access and Adherence Among Adolescent Girls and Young Women in Uganda

Prevention ICONA Dedicated Ensemble

Stick2PrEP Cisgender Women and Trans Individuals

STI Testing to Enhance PrEP Use in Pregnancy

All recent trials (100 shown)

PrEP Affect Regulation Treatment Innovation

Promoting HIV Risk Reduction Among People Who Inject Drugs: A Stepped Care Approach Using Contingency Management With Pr…

Trial phase breakdown

Trial status

Actively recruiting — 16 trials

Evaluation of mHealth Intervention to Promote HIV Prevention and Overcome Stigma Among Transgender Women (EMPOW.HER)

Adaptation of an Intervention Addressing Barriers to PrEP Use Among Pregnant Women in Zimbabwe

Suubi4PrEP: Improving PrEP Access and Adherence Among Adolescent Girls and Young Women in Uganda

Prevention ICONA Dedicated Ensemble

Stick2PrEP Cisgender Women and Trans Individuals

STI Testing to Enhance PrEP Use in Pregnancy

All recent trials (100 shown)

PrEP Affect Regulation Treatment Innovation

Promoting HIV Risk Reduction Among People Who Inject Drugs: A Stepped Care Approach Using Contingency Management With Pr…

The PrEP (Pre-exposure Prophylaxis) SMART Study

SmartSteps: A Context-Aware, PrEP Adherence Intervention for Individuals With Substance Use Disorder

Integrating Supports to Promote PrEP for Black Adolescents Working With Apps- Alabama

Integrating Supports to Promote PrEP for Black Adolescents Working With Apps- Atlanta

Linking Youth to Pre-Exposure Prophylaxis (PrEP) Services

Tu'Washindi RCT: Adolescent Girls in Kenya Taking Control of Their Health

Evaluating an Interactive Digital Toolkit for Women's PrEP Implementation

Developing mHealth to Promote PrEP Use Among Thai Young Vulnerable Adolescents and Emerging Adults

Reducing Co-occurring Substance Use and HIV Risk Among Stimulant-using Men at High Risk for HIV in the United States of…

Mental Health and Medication Adherence Among MSM in South Africa

Developing mHealth to Promote PrEP Use Among Thai Young Men Who Have Sex With Men

Phase 2b, Open Label, Multisite, Randomized Crossover Study of DPP Versus 2PR

PrEP Point-of-Care Brief-Intervention for Adherence Among Young Men Who Have Sex With Men

CARE: Comprehensive Assessment of Real-world Effectiveness of F/TAF in Persons Who Use Drugs (PWUD)

Long-Acting Injectable HIV PrEP PROs

Effect of Gum Chewing or Walking on Bowel Prep Quality and Patient Satisfaction Before Colonoscopy

Trauma Intervention to Optimize PrEP Among Women Who Inject Drugs

Pre-exposure Prophylaxis (PrEP) Adherence for Black MSM