Out-of-hospital Cardiac Arrest

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Out-of-hospital Cardiac Arrest trials you may qualify for

100

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 42 trials

RecruitingNot Applicable

NCT03981107

Compression Only CPR Versus Standard CPR in Out-Of-Hospital Cardiac Arrest - A Randomized Survival Study

Out-of-hospital cardiac arrest (OHCA) is one of the leading causes of mortality in the industrialized world. Bystander CPR before arrival of the Emergency Medic…

Italy, Sweden3,260 participantsStarted 2017-01-01

Treatment: Chest Compression Only CPR (CO-CPR) performed by trained bystanders after instructions from dispatchers, Standard CPR (S-CPR) performed by trained bystanders after instructions from dispatchers

RecruitingNot Applicable

NCT07564778

PAIN AFTER CARDIAC ARREST AND RESUSCITATION

The PAINCARE study is a substudy of the international STEPCARE trial, which investigates sedation, analgesia, and outcomes after cardiac arrest. The purpose of…

Sweden400 participantsStarted 2023-10-15

RecruitingNot Applicable

NCT07421882

PRE-hospital Cooling to improvE carDiac arrEst Neurological outComEs (PRECEDENCE)

The PRE-hospital Cooling to improvE carDiac arrEst Neurological outComEs (PRECEDENCE) study is a pilot feasibility trial evaluating the implementation of pre-ho…

Singapore50 participantsStarted 2026-02-01

Treatment: CarbonCool® Cooling Vest

RecruitingNot Applicable

NCT06844851

Evaluation of Genetic-molecular Causes of Out-of-Hospital Cardiac Arrest: From Patients to Families

The aims are to define the exact prevalence of hereditary heart diseases in out-of-hospital cardiac arrest (OHCA) patients taking also into account gender, pati…

Italy1,725 participantsStarted 2021-09-09

RecruitingPhase 2/3

NCT07239908

Resuscitation Enhancement to Avoid Rearrest Through Evidence-based Strategies in Prehospital Post-resuscitation Care

Out-of-hospital cardiac arrest (OHCA) remains a leading global emergency condition with low survival to hospital discharge despite advances in cardiopulmonary r…

Thailand318 participantsStarted 2025-12-01

Treatment: Prehospital post cardiac arrest care protocol

RecruitingNot Applicable

NCT05376267

Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)

This is a multicenter trial to establish the efficacy of cooling and the optimal duration of induced hypothermia for neuroprotection in pediatric comatose survi…

United States900 participantsStarted 2022-08-05

Treatment: Therapeutic Hypothermia

All recent trials (100 shown)

Not Yet RecruitingNot Applicable

NCT07573566

Abdominal Aortic Tourniquet Application for Non-Traumatic Out-of-Hospital Cardiac Arrest

The aim of the study is to investigate whether occluding the abdominal aorta with an external device could be a potential therapeutic option in cases of non-tra…

Austria5 participantsStarted 2026-08

Treatment: Abdominal Aortic Junction Tourniquet in non-traumatic out-of-hospital cardiac arrest

By InvitationNot Applicable

NCT04660526

RACE-CARS - RAndomized Cluster Evaluation of Cardiac ARrest Systems

RACE-CARS is a real-world cluster-randomized trial designed to evaluate a multifaceted community and health systems intervention aimed to improve outcomes of ou…

United States20,000 participantsStarted 2022-07-01

Treatment: Rapid cardiac arrest recognition that triggers immediate priority EMS/first responder dispatch by 911 operators, Systematic bystander resuscitation instruction by 911 operators

Out-of-hospital Cardiac Arrest

Trial phase breakdown

Trial status

Actively recruiting — 42 trials

Compression Only CPR Versus Standard CPR in Out-Of-Hospital Cardiac Arrest - A Randomized Survival Study

PAIN AFTER CARDIAC ARREST AND RESUSCITATION

PRE-hospital Cooling to improvE carDiac arrEst Neurological outComEs (PRECEDENCE)

Evaluation of Genetic-molecular Causes of Out-of-Hospital Cardiac Arrest: From Patients to Families

Resuscitation Enhancement to Avoid Rearrest Through Evidence-based Strategies in Prehospital Post-resuscitation Care

Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)

All recent trials (100 shown)

Abdominal Aortic Tourniquet Application for Non-Traumatic Out-of-Hospital Cardiac Arrest

RACE-CARS - RAndomized Cluster Evaluation of Cardiac ARrest Systems

Trial phase breakdown

Trial status

Actively recruiting — 42 trials

Compression Only CPR Versus Standard CPR in Out-Of-Hospital Cardiac Arrest - A Randomized Survival Study

PAIN AFTER CARDIAC ARREST AND RESUSCITATION

PRE-hospital Cooling to improvE carDiac arrEst Neurological outComEs (PRECEDENCE)

Evaluation of Genetic-molecular Causes of Out-of-Hospital Cardiac Arrest: From Patients to Families

Resuscitation Enhancement to Avoid Rearrest Through Evidence-based Strategies in Prehospital Post-resuscitation Care

Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)

All recent trials (100 shown)

Abdominal Aortic Tourniquet Application for Non-Traumatic Out-of-Hospital Cardiac Arrest

RACE-CARS - RAndomized Cluster Evaluation of Cardiac ARrest Systems

Ventilation Performance and Feedback Simulation Trial

Direct or Subacute Coronary Angiography in Patients With Out of Hospital Cardiac Arrest Without Coma.

Proteomic Analysis of Serum Samples After Cardiac Arrest: a TTM-trial Substudy

Trial of Mobile External Defibrillator for Out-of-hospital Cardiac Arrest in Singapore.

Telemedicine-Assisted vs Conventional Telephone Instruction in Cardiopulmonary Resuscitation

Relevance of Reversible Causes During OHCA (Rebecca Study)

Prehospital ETI in OHCA

The PulsePoint Study

Direct or Subacute Coronary Angiography in Out-of-hospital Cardiac Arrest

Pre-arrival Instructions Effect on Bystander Cardiopulmonary Resuscitation (CPR).

CAvent-Ventilation During Advanced Cardiopulmonary Resuscitation in Out-of-hospital Cardiac Arrest- an Observational Stu…

Pediatric Prehospital Airway Resuscitation Trial

Simulation and Feasibility Study of Drone-Delivered AED for Out-of-Hospital Cardiac Arrest

Dose-Finding Study of Intranasal Insulin in Healthy Participants Insulin in Healthy Participants

V-CARE (Virtual Care After REsuscitation)

Optimizing Ventilation to Improve Survival From Out-of-hospital Cardiac Arrest: the OPTIVO Randomized Controlled Trial

Impact of Low Dose Epinephrine in the Management of Out-of-hospital Cardiac Arrest on Neurological Outcome

Cardiac AResT And GENEtic