Opioid Abuse and Addiction

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Opioid Abuse and Addiction trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 4 trials

RecruitingPhase 1

NCT07325279

Nalmefene Implant in Healthy Subjects

The goal of this clinical trial is to learn how safe either one or two nalmefene implants are after remaining implanted for 4 or 12 weeks. Additionally the pha…

United States24 participantsStarted 2026-02-23

Treatment: 1 Nalmefene implant, 2 Nalmefene implants

RecruitingNot Applicable

NCT06837662

The MOUD Plus Pilot: Counseling and Peer Support to Support Retention for Medically Complex Patients With Opioid Use Dis…

The goal of this pilot clinical trial is to learn if a community informed designed program of addiction counseling with coordinated community peer navigator for…

United States70 participantsStarted 2025-03-24

Treatment: MOUD "Plus" Intervention (treatment as usual + coordinated counseling and referral to community based peer), Treatment As Usual (primary care with low threshold MOUD prescribing)

RecruitingPhase 2

NCT06548490

GLP-1R Agonist Treatment for Opioid Use Disorder

The goal of this clinical trial is to learn if semaglutide can reduce illicit opioid use in adults in outpatient treatment for opioid use disorder, and who are…

United States200 participantsStarted 2025-01-13

Treatment: Semaglutide Pen Injector, Placebo

RecruitingPhase 2

NCT05985850

Evaluating Tetrahydrocannabinol as an Adjunct to Opioid Agonist Therapy

This pilot study will evaluate the feasibility and safety of using 1:1 tetrahydrocannabinol (THC):Cannabidiol (CBD) cannabis oil as an adjunct therapy to methad…

Canada24 participantsStarted 2024-05-23

Treatment: Aurora 1:1 Drops (Indica), Placebo

All recent trials (46 shown)

CompletedNot Applicable

NCT03911466

Medication Treatment for Opioid Use Disorder in Expectant Mothers: Conceptual Model Assessments Sub-study

This is a sub-study of NIDA CTN Protocol 0080: Medication Treatment for Opioid Use Disorder in Expectant Mothers (MOMs; Unique protocol ID: 2019-0429-1). Partic…

United States97 participantsStarted 2020-07-21

Treatment: Buprenorphine Injection, Buprenorphine Sublingual Product

CompletedNot Applicable

NCT03911739

Medication Treatment for Opioid Use Disorder in Expectant Mothers: Infant Neurodevelopmental Outcomes Sub-study

This is a sub-study of NIDA CTN Protocol 0080: Medication Treatment for Opioid Use Disorder in Expectant Mothers (MOMs; Unique protocol ID: 2019-0429-1). Careta…

United States71 participantsStarted 2021-06-14

Treatment: Buprenorphine Injection, Buprenorphine Sublingual Product

Opioid Abuse and Addiction

Trial phase breakdown

Trial status

Actively recruiting — 4 trials

Nalmefene Implant in Healthy Subjects

The MOUD Plus Pilot: Counseling and Peer Support to Support Retention for Medically Complex Patients With Opioid Use Dis…

GLP-1R Agonist Treatment for Opioid Use Disorder

Evaluating Tetrahydrocannabinol as an Adjunct to Opioid Agonist Therapy

All recent trials (46 shown)

Medication Treatment for Opioid Use Disorder in Expectant Mothers: Conceptual Model Assessments Sub-study

Medication Treatment for Opioid Use Disorder in Expectant Mothers: Infant Neurodevelopmental Outcomes Sub-study

Trial phase breakdown

Trial status

Actively recruiting — 4 trials

Nalmefene Implant in Healthy Subjects

The MOUD Plus Pilot: Counseling and Peer Support to Support Retention for Medically Complex Patients With Opioid Use Dis…

GLP-1R Agonist Treatment for Opioid Use Disorder

Evaluating Tetrahydrocannabinol as an Adjunct to Opioid Agonist Therapy

All recent trials (46 shown)

Medication Treatment for Opioid Use Disorder in Expectant Mothers: Conceptual Model Assessments Sub-study

Medication Treatment for Opioid Use Disorder in Expectant Mothers: Infant Neurodevelopmental Outcomes Sub-study

Preventing Parental Opioid and/or Methamphetamine Addiction Within DHS-Involved Families: PRE-FAIR

Treatment Outcomes Among Patients With Prescription Narcotic Drug Use Disorder

Medication Treatment for Opioid Use Disorder in Expectant Mothers

Personally-Tailored Opioid-overdose and Medication for Opioid Use Disorder (MOUD) Education (TOME) for Pregnant and Post…

A Prospective Investigation of the Risks of Opioid Misuse, Abuse, and Addiction Among Patients Treated With Opioids for…

Treating South African Pregnant Women for Methamphetamine

The Norwegian Addiction, Pain and Trauma Study

Innovatively Increasing PCP Prescribing of Buprenorphine: Measurement Based Care and Integrated Electronic Solution

A Pragmatic Trial of the Consult for Addiction Treatment and Care in Hospitals (CATCH) Model for Engaging Patients in Op…

The Long-Term Treatment of Drug Addiction and Unemployment

Comparing Acute and Continuous Drug Abuse Treatment: A Randomized Clinical Trial

Prazosin and Naltrexone (PaN) Study for Veterans With Alcohol Use Disorders

Healthy Adult Male Facial Skin Surface Lipid Pheromone p.o. to Treat Opioid Addiction

An Observational Study to Develop Algorithms for Identifying Opioid Abuse and Addiction Based on Admin Claims Data

Study to Eval Relation Btw Doctor/Pharmacy Shopping & Outcomes of Misuse, Diversion, Abuse, Addiction by Med Rec Review

Cross-Sectional Study to Define and Validate "Doctor/Pharmacy Shopping" as Outcomes Suggestive of Abuse and/or Addiction

A Qualitative Study to Assess the Content Validity of the Prescription Opioid Misuse and Abuse Questionnaire

A Survey to Eval the Relation Between Doctor/Pharmacy Shopping and Outcomes Suggestive of Misuse, Abuse and/or Diversion