Opiate Abuse

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Opiate Abuse trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 4 trials

RecruitingPhase 2

NCT06548490

GLP-1R Agonist Treatment for Opioid Use Disorder

The goal of this clinical trial is to learn if semaglutide can reduce illicit opioid use in adults in outpatient treatment for opioid use disorder, and who are…

United States200 participantsStarted 2025-01-13

Treatment: Semaglutide Pen Injector, Placebo

RecruitingPhase 1/2

NCT06757140

Opioid Drug Interaction Study

This study will examine the effects of doses of opioid/placebo and doses of alprazolam/placebo, alone and in combination. The primary outcomes are pharmacodynam…

United States25 participantsStarted 2025-04-01

Treatment: Alprazolam, Oxycodone

RecruitingNot Applicable

NCT06453109

Focused Ultrasound for the Complex Patient

The goal of this clinical trial is to to inhibit the anterior insula (AI) with low intensity focused ultrasound (LIFU) to determine the causal role for the AI i…

United States25 participantsStarted 2024-04-29

Treatment: low intensity focused ultrasound (LIFU)

RecruitingNot Applicable

NCT00439049

Substance Abuse Pre-Treatment Screening Study

The overarching goal of this project is to have a consolidated consent and evaluation procedure that will lead potential subjects to the most appropriate clinic…

United States7,500 participantsStarted 2005-10

Treatment: modafinil, d-amphetamine

All recent trials (76 shown)

Active — Not RecruitingNot Applicable

NCT05657106

Kentucky Outreach Service Kiosk (KyOSK): Reducing HIV, HCV, and Overdose Risk

This study will test the effectiveness, implementation outcomes, and cost effectiveness of a community-tailored, harm reduction kiosk in reducing HIV, hepatitis…

United States752 participantsStarted 2023-03-06

Treatment: Harm reduction kiosk

Not Yet RecruitingNot Applicable

NCT06527079

Evaluation of Clinical Decision Support in Opioid Tapering

The 2022 Center for Disease Control and Prevention (CDC) clinical practice guideline for prescribing opioids for pain recommends that when tapering a patient's…

Location not specified200,000 participantsStarted 2026-08

Treatment: Opioid Tapering Pathway Clinical Decision Support (CDS)

Opiate Abuse

Trial phase breakdown

Trial status

Actively recruiting — 4 trials

GLP-1R Agonist Treatment for Opioid Use Disorder

Opioid Drug Interaction Study

Focused Ultrasound for the Complex Patient

Substance Abuse Pre-Treatment Screening Study

All recent trials (76 shown)

Kentucky Outreach Service Kiosk (KyOSK): Reducing HIV, HCV, and Overdose Risk

Evaluation of Clinical Decision Support in Opioid Tapering

Trial phase breakdown

Trial status

Actively recruiting — 4 trials

GLP-1R Agonist Treatment for Opioid Use Disorder

Opioid Drug Interaction Study

Focused Ultrasound for the Complex Patient

Substance Abuse Pre-Treatment Screening Study

All recent trials (76 shown)

Kentucky Outreach Service Kiosk (KyOSK): Reducing HIV, HCV, and Overdose Risk

Evaluation of Clinical Decision Support in Opioid Tapering

Medication Treatment for Opioid Use Disorder in Expectant Mothers: Infant Neurodevelopmental Outcomes Sub-study

Clinical Decision Support to Improve System Naloxone Co-prescribing

Integrated Treatment of Hepatitis C Virus Infection

Detecting Drugs of Abuse Via Exhaled Breath Samples Using Differential Mobility Spectrometry

Opioid and Cannabinoid Interactions

Intensive Models of HCV Care for Injection Drug Users

A Prospective Investigation of the Risks of Opioid Misuse, Abuse, and Addiction Among Patients Treated With Opioids for…

FAVOR Opioid Recovery Coaching Evaluation

A Project to Test the Efficacy and Safety of An Innovative Treatment for Opiate Use Disorders.

A Patient-Centered Intervention to Improve Opioid Safety

Naloxone Treatment in Skåne County - Effect on Drug-related Mortality and Overdose-related Complications

CRAFT Behavior Therapy: Treatment Entry Component

Observational Study of Misuse of High Dose Buprenorphine (Subutex® or Generic) in Opiate-Addicted Patients in France (St…

Preference for Subutex® (Buprenorphine) Versus Suboxone® (Buprenorphine/Naloxone) in Opioid Dependent Patients on Subute…

Treatment of Withdrawal Symptoms and Prevention of Relapse in Patients With Tramadol Abuse

Efficacy of Computer Delivered Community Reinforcement Approach (CRA) (Bup II)

Standardization of Post-operative Opiate Prescriptions for Same-day Ankle and Wrist Fracture Surgeries

The Effects of ∆-9-THC and Naloxone in Humans