Detecting Drugs of Abuse Via Exhaled Breath Samples Using Differential Mobility Spectrometry

Inclusion Criteria * Capable of understanding and complying with the protocol * In good physical and mental health (normal physical exam, ECG, blood and urine chemistries * Absence of history or laboratory evidence of diabetes) * Body Mass Index between 18-30, * Inclusive Age 21-50 years (age will be verified by driver's license or other valid form of identification) * Have a stable living situation with current postal address. Exclusion criteria * Meets criteria for current alcohol or substance use disorders (Past alcohol or substance use disorders greater than 3 years ago is acceptable) * Concurrent diagnosis of Axis 1 disorder be maintained on an antipsychotic or antidepressant medication * Taking prescription medications except certain short-term anti-fungal agents and some topical creams for dermal condition * Heavy alcohol drinkers (greater than 15 drinks per week) * Tobacco use greater than 5 cigarettes per day * History of major head trauma resulting in cognitive impairment or history of seizure disorder * Heavy caffeine use (greater than 500 mg on a regular daily basis) * Has active hepatitis and/or aspartate aminotransferase (AST), alanine aminotransferase (ALT)\> 3x the upper limit of normal * For female participants, a positive pregnancy test.