Myocardial Dysfunction

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Myocardial Dysfunction trials you may qualify for

100

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 44 trials

RecruitingPhase 2

NCT05583721

Relationship Between Abnormal Myocardial Perfusion and Diastolic Dysfunction in Sickle Cell Disease Using PET

There is limited information on what causes injury to the heart in individuals with Sickle Cell Disease (SCD). Researchers in this study want to see if decrease…

United States40 participantsStarted 2023-10-10

Treatment: [13N]NH3, Lexiscan

RecruitingPhase 4

NCT07168421

LANdiolol to Avoid TAchycardia in Patients at Risk for Cardiovascular Events Undergoing Major Non-cardiac Surgery

Limiting perioperative tachycardia (aiming for a heart rate \<90 beats per minute throughout the perioperative period) using the ultra-short acting beta-blocker…

Switzerland114 participantsStarted 2026-04-24

Treatment: Landiolol

RecruitingNot Applicable

NCT05427370

The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C)

The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy (STICH3C) trial is a prospective, unblinded, international multi-center randomized trial of 75…

United States754 participantsStarted 2023-06-22

Treatment: Revascularization by PCI, Revascularization by CABG

RecruitingNot Applicable

NCT07425730

Early Myocardial Dysfunction Helps Identify Severe Refractory Pediatric Lupus

To investigate biomarkers to identify pediatric SR-SLE patients by non-invasive echocardiographic techniques.

China60 participantsStarted 2026-02-01

RecruitingPhase 2

NCT06655480

Triple Combination Therapy (ARNI, SGLT2i, MRA) in Advanced HFpEF

Patients with advanced heart failure with preserved ejection fraction (HFpEF) will be randomly assigned in open-label multicenter study to receive triple combin…

Russia50 participantsStarted 2025-03-18

Treatment: [ARNI + SGLTi + AMR], [SGLTi + previously taken RAAS blocker]

RecruitingNot Applicable

NCT05365282

Association Between Radial Artery Intervention and Development of Neuropathy in the Hand - A Prospective Study

Evaluation of potential nerve damage after radial CAG/PCI.

Denmark400 participantsStarted 2024-01-01

All recent trials (100 shown)

WithdrawnPhase 1

NCT03902067

UC-MSC Transplantation for Left Ventricular Dysfunction After AMI

A pilot study to evaluate the safety and feasibility of umbilical cord mesenchymal stem cells in the treatment of acute myocardial infarction by catheter transp…

China0Started 2024-12-01

Treatment: UC-MSC, Control Group

Active — Not RecruitingNot Applicable

NCT01719016

Improvement Assessment of Coronary Flow Dysfunction Using Fundamental Fluid Dynamics

Diagnosis of relative contributions of large artery blockages and microvascular blockages is very much needed in the treatment of coronary artery disease. In or…

United States68 participantsStarted 2010-08

Treatment: Cardiac PET, Coronary catheterization

Myocardial Dysfunction

Trial phase breakdown

Trial status

Actively recruiting — 44 trials

Relationship Between Abnormal Myocardial Perfusion and Diastolic Dysfunction in Sickle Cell Disease Using PET

LANdiolol to Avoid TAchycardia in Patients at Risk for Cardiovascular Events Undergoing Major Non-cardiac Surgery

The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C)

Early Myocardial Dysfunction Helps Identify Severe Refractory Pediatric Lupus

Triple Combination Therapy (ARNI, SGLT2i, MRA) in Advanced HFpEF

Association Between Radial Artery Intervention and Development of Neuropathy in the Hand - A Prospective Study

All recent trials (100 shown)

UC-MSC Transplantation for Left Ventricular Dysfunction After AMI

Improvement Assessment of Coronary Flow Dysfunction Using Fundamental Fluid Dynamics

Trial phase breakdown

Trial status

Actively recruiting — 44 trials

Relationship Between Abnormal Myocardial Perfusion and Diastolic Dysfunction in Sickle Cell Disease Using PET

LANdiolol to Avoid TAchycardia in Patients at Risk for Cardiovascular Events Undergoing Major Non-cardiac Surgery

The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C)

Early Myocardial Dysfunction Helps Identify Severe Refractory Pediatric Lupus

Triple Combination Therapy (ARNI, SGLT2i, MRA) in Advanced HFpEF

Association Between Radial Artery Intervention and Development of Neuropathy in the Hand - A Prospective Study

All recent trials (100 shown)

UC-MSC Transplantation for Left Ventricular Dysfunction After AMI

Improvement Assessment of Coronary Flow Dysfunction Using Fundamental Fluid Dynamics

MPV as a Predictor for ACS in Patients With MASLD

Evaluation of the Systemic Microcirculation as a Surrogate for Coronary Microcirculation in Women With ANOCA

A Placebo-Controlled Trial of CLBS16 in Subjects With Coronary Microvascular Dysfunction

Comprehensive Invasive Physiological Evaluation of Obstructive Coronary Artery Disease

Microvascular Dysfunction in Patients With Long-Covid Syndrome and Angina

Dobutamine During Major Abdominal Surgery

Relationship Between Inflammatory (Hs-CRP, Neutrophil-to-Lymphocyte Ratio) and Cardiac (Troponin) Biomarkers, and Cardia…

Echocardiography Findings in Patients With Myocardial Fibrosis and Severe Aortic Stenosis

Sepsis Induced Myocardial Injury in Critically Ill Children

Evaluation of Myocardial Function by Global Longitudinal Strain (GLS) Measurement in 2D Echocardiography of Patients Wit…

RHYthm and Myocardial Function Relationship Evaluation in Heart Diseases

Effects of Nicorandil on Microvascular Dysfunction in Patients With STEMI Undergoing Primary PCI

The ENCHANTMENT HIV Study

Impella®-Supported PCI in High-Risk Patients With Complex Coronary Artery Disease and Reduced Left Ventricular Function

Self Expanding Coronary Sinus Reducer for Treatment of Symptomatic Coronary Microvascular Dysfunction (CMD)

Standardizing the Management of Patients With Coronary Microvascular Dysfunction

Effect of Intracoronary N-Acetylcysteine in Patients With ST-Elevation Myocardial Infarction Undergoing Primary Percutan…

Investigating the Clinical Benefits and Underlying Mechanisms of Danhong Injection in Modulating Mitochondrial Homeostas…