Mother to Child Transmission

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Mother to Child Transmission trials you may qualify for

100

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 10 trials

RecruitingNot Applicable

NCT06117163

Integrated Mental Health Care for Pregnant Women With HIV in Kenya: The Tunawiri Study

This study seeks to improve mental health, pregnancy, and HIV outcomes among pregnant and postpartum women living with HIV with common mental health disorders i…

Kenya900 participantsStarted 2024-10-01

Treatment: Collaborative Care Model

RecruitingPhase 4

NCT06158126

UNCPM 22314 - Pregnancy, Infant and Maternal Health Outcomes Study

The primary purpose of this study is to assess the safety of long-acting injectable cabotegravir (CAB-LA) and oral pre-expose prophylaxis (PrEP) (FTC/TDF or 3TC…

Malawi621 participantsStarted 2024-04-17

Treatment: Initiating daily oral PrEP during pregnancy, Already using daily oral PrEP at the time of pregnancy diagnosis

RecruitingNot Applicable

NCT06659315

Prevention of Mother-to-child Transmission (PMTCT) Among Women Experiencing Depression in Malawi

Prevention of mother-to-child transmission (PMTCT) of HIV virtually eliminates transmission of HIV from mothers to their infants. Adherence to PMTCT (i.e., to a…

Malawi180 participantsStarted 2025-11-11

Treatment: Couples Problem Solving Therapy

RecruitingNot Applicable

NCT07195058

Trauma-informed Obstetric Care for Perinatal Health: a Pilot Study

The study will test trauma-informed obstetric care training and supervision for obstetric clinicians in relation to prenatal mental health and attachment format…

Argentina60 participantsStarted 2025-05-23

Treatment: Trauma Informed Obstetric Care (TIOC)

RecruitingNot Applicable

NCT06493357

Evaluation of a Differentiated Point-of-care Active Case Finding & Management Model to Eliminate Mother-to-Child Transmi…

Purpose: To conduct a hybrid effectiveness-implementation stepped-wedge trial to: 1. Estimate the effect of the PAC-Man model, compared to SOC, on the proporti…

Malawi2,426 participantsStarted 2025-03-27

Treatment: PAC-Man, Standard of Care

RecruitingPhase 4

NCT05853718

Study of Tenofovir Alafenamide in HBV-Infected Pregnant Women

The purpose of this study is to evaluate the pharmacokinetics, efficacy and safety of TAF in HBV-infected pregnant women.

China50 participantsStarted 2021-05-06

Treatment: Tenofovir Alafenamide Tablets

All recent trials (100 shown)

Not Yet RecruitingNot Applicable

NCT07525076

Implementation of an Opt-Out Testing and Rapid Diagnostic Strategy for Syphilis and HIV in Pregnant Patients Presenting…

The purpose of this study is to evaluate infection detection and treatment initiation rates for syphilis and HIV before and after integration of the Chembio DPP…

United States1,400 participantsStarted 2026-04-15

Treatment: Chembio HIV/Syphilis rapid Point of Care (POC) test, Laboratory-based HIV and syphilis testing

CompletedPhase 2/3

NCT00424814

Prevention of HIV1 Mother to Child Transmission Without Nucleoside Analogue Reverse Transcriptase Inhibitors in the Pre-…

In the pre-partum phase the use of antiretroviral therapy for the mother during the last trimester of pregnancy is mandatory. The use of HAART during pregnancy,…

France105 participantsStarted 2007-03

Treatment:

Mother to Child Transmission

Trial phase breakdown

Trial status

Actively recruiting — 10 trials

Integrated Mental Health Care for Pregnant Women With HIV in Kenya: The Tunawiri Study

UNCPM 22314 - Pregnancy, Infant and Maternal Health Outcomes Study

Prevention of Mother-to-child Transmission (PMTCT) Among Women Experiencing Depression in Malawi

Trauma-informed Obstetric Care for Perinatal Health: a Pilot Study

Evaluation of a Differentiated Point-of-care Active Case Finding & Management Model to Eliminate Mother-to-Child Transmi…

Study of Tenofovir Alafenamide in HBV-Infected Pregnant Women

All recent trials (100 shown)

Implementation of an Opt-Out Testing and Rapid Diagnostic Strategy for Syphilis and HIV in Pregnant Patients Presenting…

Prevention of HIV1 Mother to Child Transmission Without Nucleoside Analogue Reverse Transcriptase Inhibitors in the Pre-…

Trial phase breakdown

Trial status

Actively recruiting — 10 trials

Integrated Mental Health Care for Pregnant Women With HIV in Kenya: The Tunawiri Study

UNCPM 22314 - Pregnancy, Infant and Maternal Health Outcomes Study

Prevention of Mother-to-child Transmission (PMTCT) Among Women Experiencing Depression in Malawi

Trauma-informed Obstetric Care for Perinatal Health: a Pilot Study

Evaluation of a Differentiated Point-of-care Active Case Finding & Management Model to Eliminate Mother-to-Child Transmi…

Study of Tenofovir Alafenamide in HBV-Infected Pregnant Women

All recent trials (100 shown)

Implementation of an Opt-Out Testing and Rapid Diagnostic Strategy for Syphilis and HIV in Pregnant Patients Presenting…

Prevention of HIV1 Mother to Child Transmission Without Nucleoside Analogue Reverse Transcriptase Inhibitors in the Pre-…

Prevention of Perinatal Transmission of HIV-1 Without Nucleoside Reverse Transcriptase Inhibitors

Spotting Syphilis: A Dual Point-of-Care Syphilis Screening Initiative in a Low-Resource Healthcare Setting

Breastmilk and the Link to Overweight/Obesity and Maternal Diet in the Mother-breastmilk-child Triad

Differentiated Service Delivery for Pregnant and Postpartum Women Living With HIV and Their Infants

The COMBAT HBV Feasibility Trial

"Pregnancy and Viral Infections: Impact on Pregnant Women and Their Children. French Prospective Cohort"

Digital Intervention to Address Stigma Among Pregnant Adolescents Living With HIV

MAGIA H3S Point of Care Test Performance for HIV, HBV, HCV, and Syphilis Screening in Pregnant Women in DR Congo

Evaluation of Problem Management Plus in Pregnant Women With HIV in Kenya

Stepped Care to Optimize PrEP Effectiveness in Pregnant and Postpartum Women

Safety and Pharmacokinetics of Dolutegravir in Pregnant HIV Mothers and Their Neonates: A Pilot Study

Healthy Mothers: an Intervention to Support Perinatal Women Living With HIV in Kenya

Becoming HIV-Exposed, Uninfected Children Born to HIV-Positive Mothers Followed at Bichat Claude Bernard Hospital

Evaluating HITSystem 2.1 to Improve Viral Suppression in Kenya

"HBV unIversal vs Point-Of-Care-based Antiviral treatMent to Prevent Mother-to-child Transmission"

Antiviral Prophylaxis and Infant Vaccination to Prevent Perinatal Hepatitis B Infection

A Study of Zidovudine/Lamivudine and Either Nevirapine or Nelfinavir for Reduction of Mother-to-child HIV Transmission D…

ARVs to Prevent Breastmilk HIV:Viral and Immune Responses