Moderate to Severe Alzheimer's Disease

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Moderate to Severe Alzheimer's Disease trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

RecruitingPhase 2

NCT06745583

A Phase 2 Study to Assess the Safety of EI-1071 and the Effects of EI-1071 on Neuroinflammation in Alzheimer's Disease P…

An open-label, exploratory, phase II, proof-of concept, clinical study to assess the safety and tolerability of EI-1071 and the effects of EI-1071 on neuroinfla…

Taiwan15 participantsStarted 2024-12-16

Treatment: EI-1071 tablet, oral

All recent trials (37 shown)

Not Yet RecruitingPhase 1

NCT07554872

Study of Neural Stem Cell-Derived Exosomes in Moderate-to-Severe Early-Onset Alzheimer's Disease

This is an open-label, single-center, phase I clinical study in patients with moderate-to-severe early-onset Alzheimer's disease. The study aims to evaluate the…

China9 participantsStarted 2026-05

Treatment: Neural Stem Cell-Derived Exosomes

Not Yet RecruitingPhase 3

NCT05303701

GV1001 Subcutaneous for the Treatment of Moderate to Severe Alzheimer's Disease(AD)

The objective of this study is to evaluate the safety and efficacy of GV1001 administered subcutaneously in patients with moderate to severe Alzheimer's disease…

Location not specified750 participantsStarted 2027-07

Treatment: GV1001 Placebo, GV1001 1.12mg

Moderate to Severe Alzheimer's Disease

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

A Phase 2 Study to Assess the Safety of EI-1071 and the Effects of EI-1071 on Neuroinflammation in Alzheimer's Disease P…

All recent trials (37 shown)

Study of Neural Stem Cell-Derived Exosomes in Moderate-to-Severe Early-Onset Alzheimer's Disease

GV1001 Subcutaneous for the Treatment of Moderate to Severe Alzheimer's Disease(AD)

Trial phase breakdown

Trial status

Actively recruiting — 1 trial

A Phase 2 Study to Assess the Safety of EI-1071 and the Effects of EI-1071 on Neuroinflammation in Alzheimer's Disease P…

All recent trials (37 shown)

Study of Neural Stem Cell-Derived Exosomes in Moderate-to-Severe Early-Onset Alzheimer's Disease

GV1001 Subcutaneous for the Treatment of Moderate to Severe Alzheimer's Disease(AD)

Satisfaction With Orodispersible vs Conventional Memantine in Moderate to Severe Alzheimer's Disease

Deep Cervical Lymphaticovenous Anastomosis Surgery for Moderate-to-Advanced Dementia Patients

Efficacy and Safety of Curcumin Formulation in Alzheimer's Disease

A Phase III Multi Regional Clinical Trial (MRCT) of Tricaprilin in Mild to Moderately Severe Probable Alzheimer's Diseas…

Vielight Neuro RX Gamma - Feasibility Pilot

Neuro RX Gamma - Pivotal Phase

Efficacy and Safety of Memantine and Sodium Oligomannate in Patients With Moderate to Severe Alzheimer's Disease

Open-Label Extension Study of 23 mg Donepezil SR in Participants With Moderate to Severe Alzheimer's Disease

Impact of Therapeutic Educational Programme on the Alzheimer's Disease Affected Patient's Quality of Life

A Study of Bryostatin in Moderately Severe to Severe Alzheimer's Disease Subjects Not On Memantine

BPDO-1603 Intervention Trial in Patients With Moderate-to-severe Alzheimer's Disease

A Randomized SAD and MAD Study Evaluating the Safety and Tolerability of RPh201 in Healthy Subjects and in Adults With A…

A 36-Week Safety Extension Study of ELND005 as a Treatment for Agitation and Aggression in Alzheimer's Disease

Efficacy and Safety Study of ELND005 as a Treatment for Agitation and Aggression in Alzheimer's Disease

A Study Assessing Bryostatin in the Treatment of Moderately Severe to Severe Alzheimer's Disease

Effectiveness of Care Management in Alzheimer Patients

Efficacy and Safety of Ramelteon in Subjects With Mild to Moderate Alzheimer's Disease

A Safety and Efficacy Study Evaluating Dimebon (Latrepirdine) in Patients With Moderate to Severe Alzheimer's Disease