Late-Onset Neonatal Sepsis

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Late-Onset Neonatal Sepsis trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 4 trials

RecruitingNot Applicable

NCT06772675

Vancomycin Reduction Practices (VRP) in the NICU

This multi-center, cluster randomized study aimed at improving implementation of vancomycin reducing practices (VRP) in neonatal intensive care units (NICUs). S…

United States13 participantsStarted 2025-06-02

Treatment: External Facilitation

RecruitingNot Applicable

NCT07152106

Amniotic Fluid & the Preterm Gut

Background: Necrotizing enterocolitis (NEC) and sepsis in preterm infants have been linked to intestinal immaturity and preclinical gut microbiota alterations.…

Netherlands275 participantsStarted 2024-10-14

RecruitingNot Applicable

NCT06058819

Validation of Biomarkers Performance to Reduce Antibiotics overUse in newBorns With Suspected Clinical Signs of Infectio…

Late-onset neonatal sepsis (LOS), occurring in newborn of at least 7 days of life, is frequently observed in Neonatal Intensive Care Units (NICUs) and potential…

France358 participantsStarted 2023-11-22

Treatment: Newborns suspected of Infections

RecruitingNot Applicable

NCT05347238

Dopamine vs. Norepinephrine for Hypotension in Very Preterm Infants With Late-onset Sepsis

Fluid-unresponsive hypotension needing cardiotropic drug treatment is a serious complication in very preterm neonates with suspected late-onset sepsis (LOS; def…

United States, Canada550 participantsStarted 2023-02-06

Treatment: Dopamine, Norepinephrine

All recent trials (52 shown)

CompletedPhase 4

NCT03997266

NICU Antibiotics and Outcomes Trial

The goal of the NANO trial is to study the longstanding clinical practice of empirically administering intravenous antibiotics to extremely low birthweight (ELB…

United States359 participantsStarted 2020-08-05

Treatment: Ampicillin, Gentamycin

Active — Not RecruitingPhase 4

NCT07248761

Early Hydrocortisone Versus Regular Treatment in Shock in Extremely Preterm Neonates - an Open Randomized Controlled Tri…

The goal of this clinical trial is to determine the effectiveness of early use of hydrocortisone (since the diagnosis of shock) for its resolution within the fi…

Mexico76 participantsStarted 2025-02-01

Treatment: Intravascular Hydrocortisone (stress dosage): 1 mg/k/dose each 8 hours for 5 days, Vasoactive drug therapies

Late-Onset Neonatal Sepsis

Trial phase breakdown

Trial status

Actively recruiting — 4 trials

Vancomycin Reduction Practices (VRP) in the NICU

Amniotic Fluid & the Preterm Gut

Validation of Biomarkers Performance to Reduce Antibiotics overUse in newBorns With Suspected Clinical Signs of Infectio…

Dopamine vs. Norepinephrine for Hypotension in Very Preterm Infants With Late-onset Sepsis

All recent trials (52 shown)

NICU Antibiotics and Outcomes Trial

Early Hydrocortisone Versus Regular Treatment in Shock in Extremely Preterm Neonates - an Open Randomized Controlled Tri…

Trial phase breakdown

Trial status

Actively recruiting — 4 trials

Vancomycin Reduction Practices (VRP) in the NICU

Amniotic Fluid & the Preterm Gut

Validation of Biomarkers Performance to Reduce Antibiotics overUse in newBorns With Suspected Clinical Signs of Infectio…

Dopamine vs. Norepinephrine for Hypotension in Very Preterm Infants With Late-onset Sepsis

All recent trials (52 shown)

NICU Antibiotics and Outcomes Trial

Early Hydrocortisone Versus Regular Treatment in Shock in Extremely Preterm Neonates - an Open Randomized Controlled Tri…

Procalcitonin and Duration of AntiBiotherapy In Late Onset Sepsis of Neonate

Evaluation of bioMarkErs to Reduce Antibiotics Use in hospitalizeD nEonates

Late-onset Sepsis in Term and Pre-term Neonates and Infants up to 3 Months of Age

Markers of Platelet Activation foR Identification of Late Onset Sepsis in Preterm Infants

Late-onset Sepsis and Development

Enrichment of Human Milk With Human and Bovine Milk-based Fortifiers for Very Preterm Infants: a Meta-analysis

Serosurveillance Study of Maternally Derived Anti-GBS Antibody

Pentoxifylline Dose Optimization in Neonatal Sepsis

Using Machine Learning to Model Early-onset Neonatal Sepsis Risk in Uganda and Zimbabwe

The High Initial Dose of Monitored Vitamin D Supplementation in Preterm Infants.

Maternal, Neonatal and Infant Outcomes at Kawempe National Referral Hospital

The Effect of Probiotics Added to the Mother's Diet on Preterm Babies

Serocorrelate of Protection Against GBS (PREPARE WP3)

Clinical Impact of Donor Milk Pasteurized by HTST Treatment in Preterm Infants

Topical Coconut Oil Application and Incidence of Sepsis in Neonates

Effect of Kangaroo Care on Heart Rate Variability in Late-onset Neonatal Sepsis

Probiotics and the Neurodevelopment in the Premature Infant <32 Weeks Gestational Age and <1500g

Model-based Dose Versus Empirical Dose of Piperacillin/Tazobactam in Preterm Neonates With Late-onset Sepsis.