CompletedNot Applicable

Markers of Platelet Activation foR Identification of Late Onset Sepsis in Preterm Infants

Ireland268 participantsStarted 2022-09-02

Plain-language summary

The PARENT study will examine platelet and endothelial associated proteins in preterm infants being investigated for late onset sepsis (LOS) to see if infants with fulminant sepsis can be prospectively identified using these markers

Who can participate

Age range34 Weeks

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * \<34 weeks corrected gestational age at birth * Under investigation for Late Onset Neonatal Sepsis (Sepsis of onset \>72 hours of age) Exclusion Criteria: * Major congenital anomaly * Suspicion of an underlying haematological disorder affecting platelets * Have received a platelet transfusion prior to sampling

What they're measuring

A difference exists between infants with culture proven late onset sepsis and those without in platelet and endothelial proteomic profiles

Timeframe: 3 years

Trial details

NCT IDNCT05530330

SponsorUniversity College Dublin

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-02-28

View on ClinicalTrials.gov More Late-Onset Neonatal Sepsis trials