Hypotension and Shock

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Hypotension and Shock trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 13 trials

RecruitingPhase 4

NCT05836610

Hydrocortisone Therapy Optimization During Hypothermia Treatment in Asphyxiated Neonates

This is a prospective, single center, pharmacokinetic study of intravenous hydrocortisone therapy for systemic low blood pressure during hypothermia treatment i…

Hungary50 participantsStarted 2021-09-21

Treatment: Hydrocortisone

RecruitingNot Applicable

NCT07068022

Organ Dysfunction Score for Obstetric Patients

The goal of this observational study is to develop and evaluate an organ dysfunction score adapted to pregnancy and early puerperium (SOFA-OBS) that also incorp…

Argentina130 participantsStarted 2025-10-06

Treatment: Organ dysfunction score adjusted to obstetric patients (SOFA-OBS)

RecruitingNot Applicable

NCT07343206

Early Norepinephrine Administration and Rapid Dose Adjustment

The goal of this clinical trial is to determine whether early initiation of norepinephrine with rapid dose adjustment improves clinical outcomes in adult patien…

Thailand600 participantsStarted 2026-01-01

Treatment: Early norepinephrine administration and rapid dose adjustment, Control

RecruitingNot Applicable

NCT07499947

Predicting Spinal Hypotension in Cesarean Section

This prospective observational study investigates the predictive value of anthropometric and hemodynamic indices for spinal anesthesia-induced hypotension (SAIH…

Turkey (Türkiye)321 participantsStarted 2026-03-16

RecruitingNot Applicable

NCT07500519

Preoperative Shock Indexes and Post-Spinal Hypotension in Cesarean Surgery

This prospective observational study aims to evaluate the predictive performance of preoperative Shock Index (SI) and Modified Shock Index (MSI) for hypotension…

Turkey (Türkiye)300 participantsStarted 2025-10-15

RecruitingPhase 4

NCT05168462

Clinical Outcome and Cost-effectiveness of Reduced Noradrenaline by Using a Lower Blood Pressure Target in Patients With…

Rationale: Pump failure due to acute myocardial infarction (AMI) can lead to cardiogenic shock (CS): a state of low blood flow to end-organs with subsequent mul…

Netherlands776 participantsStarted 2022-10-01

Treatment: Reduced noradrenaline use

All recent trials (85 shown)

CompletedPhase 2

NCT05092165

Methylene Blue for the Prevention of Hypotension During Hemodialysis

Hypotension is a common complication of intermittent renal replacement therapy. Methylene blue, an inhibitor of nitric oxide synthesis, has been suggested to im…

Brazil261 participantsStarted 2021-10-21

Treatment: Methylene Blue, Control

Not Yet RecruitingNot Applicable

NCT07530653

Delayed Fluids in Hemorrhagic Shock Due to Severe Injuries.

This study will provide information on the quality of care in hemorrhagic shock of severe injuries in a limited resource facility of Latin America, the strategi…

Colombia716 participantsStarted 2026-10-01

Treatment: Crystalloid below 1000 mL., IV fluids more than 1,000 mL

Hypotension and Shock

Trial phase breakdown

Trial status

Actively recruiting — 13 trials

Hydrocortisone Therapy Optimization During Hypothermia Treatment in Asphyxiated Neonates

Organ Dysfunction Score for Obstetric Patients

Early Norepinephrine Administration and Rapid Dose Adjustment

Predicting Spinal Hypotension in Cesarean Section

Preoperative Shock Indexes and Post-Spinal Hypotension in Cesarean Surgery

Clinical Outcome and Cost-effectiveness of Reduced Noradrenaline by Using a Lower Blood Pressure Target in Patients With…

All recent trials (85 shown)

Methylene Blue for the Prevention of Hypotension During Hemodialysis

Delayed Fluids in Hemorrhagic Shock Due to Severe Injuries.

Trial phase breakdown

Trial status

Actively recruiting — 13 trials

Hydrocortisone Therapy Optimization During Hypothermia Treatment in Asphyxiated Neonates

Organ Dysfunction Score for Obstetric Patients

Early Norepinephrine Administration and Rapid Dose Adjustment

Predicting Spinal Hypotension in Cesarean Section

Preoperative Shock Indexes and Post-Spinal Hypotension in Cesarean Surgery

Clinical Outcome and Cost-effectiveness of Reduced Noradrenaline by Using a Lower Blood Pressure Target in Patients With…

All recent trials (85 shown)

Methylene Blue for the Prevention of Hypotension During Hemodialysis

Delayed Fluids in Hemorrhagic Shock Due to Severe Injuries.

Trendelenburg as a First-line Intervention in Critically Ill, Sedated, Invasively Mechanically Ventilated, Hypotensive P…

Novel Predictors of Post Spinal Hypotension in Cesarean Sections: Evaluating Jugular Vein Collapsibility Index and Shock…

Synthetic Angiotensin II/Giapreza in Pediatric Patients With Refractory Hypotension

Midodrine Use in Septic Shock

Cerebral Circulation in Critically Ill Children

Volume Resuscitation in Cirrhosis With Sepsis Induced Hypotension

Non-Invasive Cardiac Output Monitor (NICOM) for Goal-directed Fluid Resuscitation for Inpatients With Hypotension and/or…

Use of Ultrasonography to Determine Fluid-responsiveness for Shock in a Population of Intensive Care Unit Patients

Comparison of Pleth Variability Index vs. Diastolic Shock Index for Predicting Hypotension During Anesthesia Induction

Hypotension in the Weaning From Vasopressor Drugs

BP Management System User Acceptance Testing

Restricted or Liberal Fluid for Haemodynamic Resuscitation in Sepsis

Fluid Balance in the ICU - Interventions to Minimize Fluids in Patients With Septic Shock

Using Vasopressor Medication to Support Blood Pressure During Intubation Procedure

Intravenous AII for the Treatment of Severe Hypotension in High Output Shock: A Pilot Study

BCG Biosensor and Non- and Invasive Monitoring During Emergency Medicine Cases, a Prospective Feasibility Study

Norepinephrine Administration Through a Midline Catheter in an Intermediate Care Unit

Pragmatic Randomized Trial for Arterial Catheters in the Critical Care Environment