CompletedNot Applicable

Fluid Balance in the ICU - Interventions to Minimize Fluids in Patients With Septic Shock

82 participantsStarted 2014-01

Plain-language summary

The purpose of the study is to determine if a protocol that assesses patients' daily fluid intake and output can decrease the overall amount of fluid patients receive during the first five days in the ICU. The study will also determine if decreasing overall fluids can decrease adverse events associated with mechanical ventilation, such as ventilator-associated pneumonias. The protocol will include daily ultrasounds and blood draws to evaluate fluid balance. Ultrasound will be used to measure changes in the diameter of the inferior vena cava with respiration.

Who can participate

Age range18 Years – 89 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Adult patient with septic shock as the primary cause of hypotension
✓. Requiring vasopressors for 12 hours after adequate fluid resuscitation and at the time of enrollment

Exclusion criteria

✕. Patients with a history of end-stage renal disease requiring outpatient dialysis
✕. Patients whose goals of care are consistent with comfort measures only
✕. Pregnant patients

What they're measuring

Cumulative Fluid Administered

Timeframe: Day 3

Cumulative Fluid Administered

Timeframe: Day 5

Net Fluid Balance

Timeframe: Day 3

Net Fluid Balance

Timeframe: Day 5

Trial details

NCT IDNCT02473718

SponsorWashington University School of Medicine

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2014-12

Results submitted2018-01-31

View on ClinicalTrials.gov More Septic Shock trials